Pharmacophore an International Research Journal
Pharmacophore
Submit Manuscript
Open Access | Published: 2023 - Issue 4

 

A REVIEW OF THE ROLE OF COGNITIVE-BEHAVIORAL THERAPY ON ANXIETY DISORDERS OF CHILDREN AND ADOLESCENTS

Nicolae Dumitru Nicoară1, Paula Marian2,3*, Alin Ovidiu Petriș3, Cristian Delcea4, Felicia Manole3,5

 

  1. Doctoral School of Biomedical Sciences, Faculty of Medicine and Pharmacy, University of Oradea, 410087 Oradea, Romania.
  2. Department of Medical Discipline, Faculty of Medicine and Pharmacy, University of Oradea, 410087 Oradea, Romania.
  3. County Clinical Emergency Hospital of Oradea, 410087 Oradea, Romania.
  4. Department of Forensic Medicine, "Iuliu Hațieganu" University of Medicine and Pharmacy, 400000 Cluj-Napoca, Romania.
  5. Department of Surgical Discipline, Faculty of Medicine and Pharmacy, University of Oradea, 410087 Oradea, Romania.

 


ABSTRACT

Anxiety disorders are among the most prevalent illnesses in children and adolescents. Children and teens who have these problems perform less well in school, at home, and in social situations. It is crucial to determine the best behavioral and psychiatric therapies for these illnesses. Given the significance of the aforementioned subject, this study looked at how well cognitive-behavioral therapy treats anxiety problems in children and adolescents. Most of the reviewed research contained methodological and theoretical problems. Several challenges included the following: the existence of weaknesses and deficiencies in comparing the results with previous similar studies, the weak explanations provided, the small sample size, and the lack of reference to monitoring methods and advanced formulas of statistics. The majority of the studies under examination did not accurately present and report the data according to the worldwide standard for clinical trials principles and standards. The findings of the studies under review indicate a weak to moderate effectiveness of intervention protocols, but it appears that if the theoretical and methodological issues are resolved, a more precise assessment of the efficacy of cognitive behavioral therapy for anxiety disorders in children and adolescents can be made.

Keywords: Adolescents, Cognitive-behavioral therapy, Children, Anxiety disorders


Introduction

One of the most prevalent psychiatric illnesses in children and adolescents is anxiety disorders, whose prevalence in people under 18 years is between 3 and 27% [1-5]. Anxiety disorders in children are classified as internalizing disorders. Internalizing disorders are maladaptive behavior patterns that cause the child's resentment rather than bothering the people around them [6, 7]. Although a certain amount of anxiety is needed for effective performance, high anxiety causes helplessness and disrupts relationships with friends and family in school assignments [8, 9]. Children with anxiety disorders react strongly to stimuli, which they consider tense states and negative and continuous emotional responses. Since these children have defects in regulating their emotions, this leads to an increase in interpersonal problems between these people. Anxiety disorders have high comorbidity with other disorders, including attention deficit hyperactivity disorder (about 04.04 comorbidity), oppositional defiant disorder (about 43.9), and obsessive-compulsive disorder (about 61.8) [10-12]. According to the chronic course of anxiety disorders in childhood and adolescence and their continuation in the growth path, depending on certain influencing factors such as genetic background, family history, parent's anxiety, type of attachment to the caregiver, learning, experience, and parenting style. It is the cause of disorders in adulthood [13-15].

Considering the importance of the issue, it is necessary to diagnose and treat anxiety disorders in childhood and adolescence. The most common anxiety disorders in this age group are generalized anxiety disorder, separation anxiety disorder, and social anxiety disorder [3, 16]. The main characteristic of generalized anxiety disorder is persistent anxiety and uncontrollable worry that can be seen on most days during 6 months [17, 18]. Symptoms of a generalized anxiety disorder include restlessness, aggression, muscle contraction, fatigue and sleep disturbances, and problems in concentration [19, 20]. This disorder has received a lot of attention in terms of the important role of worry in creating dysfunctional emotional processing. In explaining the etiology of this disorder, Barlow points to two main factors: General Psychological Vulnerability and General Biological Vulnerability [21]. Psychological vulnerability refers to the factor of uncontrollability. The perception of uncontrollability causes the formation of a belief based on the inability to influence events. Such beliefs make people susceptible to anxiety disorders. On the other hand, parents' discordant behavior leads to a decrease in the child's ability to predict the parents' reactions and ultimately leads to children's behavioral inhibition. Failure to control external threats or failure to control internal threats is the main problem during anxiety [22-24]. The classic anxiety disorder of childhood, which is known as separation anxiety disorder or attachment disorder, has a prevalence of about 6-18%. This disorder makes the child prone to anxiety disorder in adolescence and early adulthood [25]. The results of longitudinal studies on separation anxiety in children between 1.5 and 6 years old showed that most children with separation anxiety disorder gradually recover at the age of 4-5 years [26]. But factors such as anxiety and depression of the mother during pregnancy and unemployment of the parents cause the continuation of this disorder, which continues until adulthood if not treated. According to these cases, it is necessary to emphasize preventing the continuation and growth of separation anxiety disorder until preschool age [19]. This disorder, which is often characterized by depression and externalizing disorders and with early onset in childhood, without proper treatment may lead to other anxiety disorders and negative performance in various aspects of adult life over time. Social anxiety disorder starts as early as 8 years old. The clinical manifestations and destructive consequences of this disorder gradually appear in childhood and intensify in early or middle adolescence [27]. Approximately 75% of people experience symptoms between the ages of 8-15 years [28]. The 12-month prevalence of this disorder in children and adolescents, like adults, is about 7% [29]. Social anxiety disorder has high comorbidity with other anxiety and mood disorders, disruptive behaviors, and eating disorders. Research has shown that 81% of people with social anxiety disorder also have another disorder. Depression is one of the most common mental disorders that has a high correlation with social anxiety disorder among teenagers. Therefore, early intervention is necessary to prevent long-term adverse consequences of this disorder [30].

There are many treatment programs for the treatment of children's anxiety disorders, most of which have a cognitive-behavioral basis. In the field of anxiety disorders, especially in the case of children and adolescents, cognitive and behavioral therapy is the chosen and evidence-based treatment in the research literature, and this treatment is also considered here. Cognitive behavioral therapy’s effect on reducing anxiety symptoms in children has been well shown in research [15, 31-33]. Cognitive-behavioral therapies can modify thinking since the fundamental tenet of cognitive-behavioral therapy is that cognition is essentially the source of feelings and behavior [34]. In this treatment, there are two cognitive strategies, such as discovering cognitive distortions and anxiety-provoking thoughts, cognitive reconstruction and strengthening fruitful confrontational self-talk, and behavioral strategies such as role modeling, confrontation, role-playing, muscle relaxation, coping skills training, and increasing self-control and self-efficacy are used [34, 35]. The therapist teaches the child coping skills and creates circumstances for him to practice them, as is indicated in cognitive behavioral therapy. These abilities help youngsters who have anxiety issues. Cognitive behavioral therapy employs a variety of strategies, such as educating the kid and parents about anxiety, progressive muscle relaxation exercises, deep breathing exercises, and challenging thoughts that cause anxiety (cognitive retraining by exposing the child to anxiety), relapse prevention like motivational sessions, and collaboration with parents and school [36, 37]. Treating anxiety in children not only reduces anxiety symptoms but also extends to the treatment of depressive symptoms and externalizing behaviors in the child and thus strengthens the child's adaptive functioning. There are many treatment protocols for the treatment of anxiety disorders. The articles reviewed in this study include some of these protocols, including the confrontational cat protocol [38], group cognitive-behavioral therapy (CBGT) [39], reassurance therapy package, cognitive-behavioral therapy method with a single-process approach [40], and Mykniam's cognitive therapy method [41]. Considering the importance of the mentioned topic, the impact of cognitive-behavioral treatment on anxiety disorders in children and adolescents was studied in this study.

Results and Discussion

In research that looked at how cognitive behavioral therapy affected teenage females with generalized anxiety disorder in terms of anxiety reduction, the findings revealed that following cognitive-behavioral treatment, the anxiety of the experimental group of adolescents dramatically decreased. This demonstrated the efficacy of the therapy [37]. Another study looked at how family-focused cognitive-behavioral treatment affected anxiety in kids with anxiety disorders. Its results indicated that the percentage of recovery for 3 children in one-month follow-up is 86, 41, and 60 [42]. Secondary research compared the efficacy of cognitive-behavioral group therapy (CBT) and emotion-oriented cognitive-behavioral group therapy (ECBT) on children with social anxiety disorder. The results of this study showed that both treatments were effective in reducing the symptoms of social anxiety and dysregulation of sadness in affected children compared to the control group. However, in the scores of grief dysregulation in the follow-up three months later, only emotion-oriented therapy was effective in reducing grief dysregulation compared to the control group; In fact, the effects of change therapy (ECBT) have been stable over time on this variable. Also, in this study, in the variables of inhibition of anger and sadness and effective coping with anger and sadness, only emotion-oriented therapy affected the dependent variable [24].

In a study, it was determined whether cognitive-behavioral group treatment helped generalized anxiety disorder sufferers aged 11 to 13 feel more in control of their anxiety, cognitive-behavioral therapy based on the Coping Cat therapy guide was effective in increasing the perception of emotion and stress control. It was a transition, but it did not have much effect on the threat control. The effect size of treatment on emotion control, threat control, and stress control was 11.25, 0, and 0.29, respectively [11]. In another study, the effectiveness of cognitive-behavioral therapy based on the program (Coping Cat) in reducing the anxiety of 8- to 10-year-old children was investigated. The effect size of the treatment group was 2.3 and the effect size of the waiting group was estimated to be 0.26. Based on these estimates, the changes in 70-80% of subjects were clinically significant [15]. Another research was carried out to see if the confrontational cat therapy program might help youngsters with their anxiety problems. The effect size for the social anxiety variable was 0.33, separation anxiety was 0.33, fear of injury was 0.28, and physical symptoms were 0.32 [36].

The average anxiety score of the control group for boys was 9 when cognitive-behavioral treatment centered on the processing unit (MCBT) was examined to see if it may help children aged 6 and 7 with their separation anxiety symptoms whereas, for cognitive-behavioral therapy with the unit-process approach E is equal to 5.4 and the average score of the control group for girls is 558.10 and for the treatment group is 5.063. Also, the partial coefficient of the eta square was reported as 0.409 [33]. Additionally, when cognitive-behavioral group therapy was tested for its efficacy in treating children with generalized anxiety disorder, the results revealed that it is useful in lowering anxiety, eradicating unhelpful schema, and enhancing family ties [11]. A meta-analysis of psychological interventions for treating children and adolescents with social anxiety disorder showed that the effect size for cognitive-behavioral treatments is 0.24 and the effect size for correcting interpretation biases is 0.48. Therefore, it was concluded that psychological treatments are effective in reducing social anxiety in children and adolescents [30].

In examining the effectiveness of cognitive-behavioral group therapy on anxiety and fatigue in girls with generalized anxiety disorder, the results showed that this treatment had an effect on the anxiety level of the subjects, but did not affect the fatigue component. Also, there was no significant difference in the level of fatigue between the two experimental and control groups in three measurement levels [19]. Also, the results of a study that examined the effectiveness of cognitive-behavioral therapy on social anxiety and blood sugar control in children with type 1 diabetes mellitus showed that cognitive-behavioral therapy according to the average social anxiety components of the experimental group in the post-test Compared to the average of the control group, it has reduced the social anxiety of the experimental group [43]. When evaluating the efficacy of narrative therapy for the anxiety of elementary school girls, it was found that: story therapy was able to significantly reduce generalized anxiety and social anxiety [44]. In research that looked at how group cognitive-behavioral therapy affected female students' social anxiety, the findings confirmed with 99% confidence the hypothesis of the research that group cognitive-behavioral therapy is effective on social anxiety [45]. Additionally, research into group cognitive-behavioral therapy's efficacy for enhancing the quality of life and academic performance of middle school male students with generalized anxiety disorder revealed that this treatment is successful in improving the quality of life and its components. It also had a positive impact on these students' academic performance [46].

Conclusion

Considering the high and stable prevalence of anxiety disorders in childhood and adolescence, their relationship with social and academic performance deficits, effective, timely prevention, and intervention programs for this special group of children are very important. Since one of the important treatment approaches in the field of anxiety disorders is cognitive-behavioral therapy, this study aimed to review the studies conducted in connection with the effect of this treatment on the improvement of anxiety disorders in children and adolescents. The findings of research that looked at how well cognitive-behavioral group therapy treats anxiety disorders and their symptoms are consistent with one another and support the effectiveness of CBT in treating anxiety. In the studies that used individual cognitive-behavioral therapy, half of the studies used the therapy protocol (Coping Cat). All the reviewed studies reported the effectiveness of this treatment and the range of the effect size of most of the studies was in the range of 0.15 to 0.48 and there was no great difference between them.

Acknowledgments: None

Conflict of interest: None

Financial support: None

Ethics statement: None

References

  1. Costello EJ, Angold A, Burns BJ, Stangl DK, Tweed DL, Erkanli A, et al. The great smoky mountains study of youth. Goals, design, methods, and the prevalence of DSM-III-R disorders. Arch Gen Psychiatry. 1996;53(12):1129-36.
  2. Yousaf M, Khan MM, Paracha AT. Leading professionally diverse workgroups of healthcare professionals for improving quality of care. J Organ Behav Res. 2021;6(1):106-19.
  3. Sarraf N, Mohammadi MR, Ahmadi N, Khaleghi A, Gharibi S, Atapour H. Epidemiology of children and adolescents psychiatric disorders in Qazvin central areas 2016-2017 (A National Project). J Inflammat Dis. 2019;22(6):164-76.
  4. Hassan HH. A Training program on emotional adjustment and its social communication effect in children with behavioral disorders. J Organ Behav Res. 2021;6(1):203-19.
  5. Haghbin A, Mohammadi M, Ahmadi N, Khaleghi A, Golmakani H, Kaviyani F, et al. Prevalence of psychiatric disorders in children and adolescents of north Khorasan province, Iran. J North Khorasan Univ Med Sci. 2018;10(1):117-27.
  6. Tehranizadeh M, Dadsetan PR, Tabatabaee K, Azad Fallah P, Fathi Ashtiani A. Effectiveness of the coping cat therapy program in decreasing internalized symptoms of Iranian children. J Dev Psychol. 2011;7(28):313-21.
  7. Nguyen KN, Do TD. Factors influencing knowledge sharing in higher education: An empirical study of students in Vietnam. J Organ Behav Res. 2021;6(2):134-51.
  8. Kendall PC, Compton SN, Walkup JT, Birmaher B, Albano AM, Sherrill J, et al. Clinical characteristics of anxiety disordered youth. J Anxiety Disord. 2010;24(3):360-5.
  9. Salhi B. Effect of the mandatory adoption of IFRS on the quality of accounting information: Case of France. J Organ Behav Res. 2021;6(2):152-60.
  10. Bhardwaj M, Kapila R, Neha A, Jain R, Mittal P, Suri M. Awareness, perceived risk, and protective behavior towards Covid-19 among undergraduate students of Delhi and NCR, India. Int J Pharm Res Allied Sci. 2022;11(3):71-80.
  11. Torabi Mazreh Malaki N, Tahmasian K, Bakhtyari M, Ghamkhar Fard Z, Amrolahinia M. The effectiveness of Group cognitive-behavioral therapy in increasing of perceived anxiety control in 11-13 girls with generalized anxiety disorder (GAD). J Psychol Stud. 2015;11(1):29-50.
  12. Sawad AB, Andrews K. General theory of marketing ethics and unethical behavior in the pharmaceutical industry field. Int J Pharm Res Allied Sci. 2021;10(3):120-8.
  13. Khakpoor S, Saed O. Transdiagnostic cognitive behavioral therapy based on unified protocol: new approach to emotional disorders. Asia Pacific J Clinic Trial Nervous Sys Dis. 2018;3(4):151.
  14. Alharthy BT, Sajini SI. Assessment of attitude knowledge and skills among senior dental undergraduates on substance use disorder (SUD). Int J Pharm Res Allied Sci. 2021;10(3):120-8.
  15. Zarghami F, Heidari Nasab L, Shaeiri MR, Shahrivar Z. A study in the impact of coping-cat-based cognitive-behavior therapy (CBT) on reduced anxiety in the children aged 8 to 10 with anxiety disorder. Clin Psychol Stud. 2015;5(19):183-202.
  16. Solyeyko O, Tsarenko S, Chernykh M, Berezovskiy A, Soleyko L, Fedorchenko O, et al. Integrative art-therapeutic correction of psychosomatic disorders in children with undifferentiated connective tissue dysplasia. Arch Pharm Pract. 2023;14(1):63.
  17. Rashtbari A, Saed O. Contrast avoidance model of worry and generalized anxiety disorder: A theoretical perspective. Cogent Psychol. 2020;7(1):1800262.
  18. Elsawy A, Alkhalaf R, Binnjefan S, Alkhalaf K, Alhumaidan S, Haridy R. Temporomandibular disorders: A cross sectional study into the knowledge and awareness among Saudi Arabian population. Arch Pharm Pract. 2022;13(3):116-21.
  19. GhamkharFard Z, Bakhtiari M, Hajiheidari Z, Pouravari M, Tahmasian K. The effectiveness of group cognitive-behavioral therapy in anxiety and boredom proneness in generalized anxiety disorder girls. Knowledge Res Appl Psychol. 2019;20(3):122-32.
  20. Bibi N, Wara B, Morrissey H, Ball P. Impact of mental III Health on medication adherence behaviour in patients diagnosed with type 2 diabetes. Arch Pharm Pract. 2021;12(4):6-16.
  21. Chorpita BF, Barlow DH. The development of anxiety: the role of control in the early environment. Psychol Bull. 1998;124(1):3-21.
  22. Khakpoor S, Mohammadi Bytamar J, Saed O. Reductions in transdiagnostic factors as the potential mechanisms of change in treatment outcomes in the Unified Protocol: A randomized clinical trial. Res Psychother. 2019;22(3):379.
  23. Khakpoor S, Saed O, Armani Kian A. Emotion regulation as the mediator of reductions in anxiety and depression in the Unified Protocol (UP) for transdiagnostic treatment of emotional disorders: Double-blind randomized clinical trial. Trends Psychiatry Psychother. 2019;41(3):227-36.
  24. Afshari A, Amiri S, Neshat Doost HT, Rezaie F. Comparing effectiveness of group emotion-focused cognitive-behavioral therapy and group cognitive-behavioral therapy on children with social anxiety disorder. Stud Med Sci. 2015;26(3):194-204.
  25. Eisen AR, Schaefer CE. Separation anxiety in children and adolescents: An individualized approach to assessment and treatment: Guilford Press; 2007.
  26. Fakunmoju SB, Bammeke FO. Anxiety disorders and depression among high school adolescents and youths in Nigeria: Understanding differential effects of physical abuse at home and school. J Adolesc. 2015;42:1-10.
  27. Khakpoor S, Saed O, Shahsavar A. The concept of "Anxiety sensitivity" in social anxiety disorder presentations, symptomatology, and treatment: A theoretical perspective. Cogent Psychol. 2019;6(1):1617658.
  28. Kessler RC, Chiu WT, Demler O, Walters EE. Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication. Arch General Psychiatr. 2005;62(6):617-27.
  29. American Psychiatric Association A. Diagnostic and statistical manual of mental disorders: American Psychiatric Association Washington, DC, 1980.
  30. Jahanbakhshi Z, Borjali A, Farahbakhsh F, Falsafinejad M, Shariatmadar A. A meta-analysis of psychological treatment for reducing social anxiety disorder in children and teenagers. J School Psychol. 2018;7(2):33-53.
  31. Momeni F, Shahidi S, Mootabi F, Heydari M. Comparison of the Effectiveness between cognitive-behavior group therapy and mindfulness based cognitive therapy on females with generalized anxiety disorder. Clin Psychol Stud. 2018;8(32):93-111.
  32. Pirnia B, Rasoulzadeh Tabatabaei SK, Pirkhaefi A, Soleimani A. Comparison of the effectiveness of two cognitive-behavioral and mother-child interactive therapies on anxiety of children with under-methadone treatment mother. Iran J Psychiatr Clinic Psychol. 2017;23(2):136-47.
  33. Abdkhodaie MS, Sadeghi Ardobadi A. Prevalence of separation anxiety in children and effect of cognitive behavioral play therapy on reducing it. J Clin Psychol. 2011;3(4):51-8.
  34. Roohi A. Theoretical and applicable approaches in anxiety disorders in children. Except Educat. 2014;3(125):47-58.
  35. Labellarte MJ, Ginsburg GS, Walkup JT, Riddle MA. The treatment of anxiety disorders in children and adolescents. Biol Psychiatr. 1999;46(11):1567-78.
  36. Shokri MH, Alizade H, Farrokhi N. The impact of coping cat program on symptoms reduction in children with anxiety disorders. Q J Child Ment Health. 2018;5(2):1-3.
  37. AliRezai Motlaq M, Asadi Z. Cognitive-behavioral therapy (CBT) in ameliorating adolescent anxiety in generalized anxiety disorders (GAD). J Except Child. 2009;9(1):25-34.
  38. Kendall PC, Flannery-Schroeder E, Panichelli-Mindel SM, Southam-Gerow M, Henin A, Warman M. Therapy for youths with anxiety disorders: a second randomized clinical trial. J Consult Clin Psychol. 1997;65(3):366-80.
  39. Heimberg RG, Liebowitz MR, Hope DA, Schneier FR, Holt CS, Welkowitz LA, et al. Cognitive behavioral group therapy vs phenelzine therapy for social phobia: 12-week outcome. Arch Gen Psychiatry. 1998;55(12):1133-41.
  40. Silverman WK, Pina AA, Viswesvaran C. Evidence-based psychosocial treatments for phobic and anxiety disorders in children and adolescents. J Clin Child Adolesc Psychol. 2008;37(1):105-30.
  41. Corey G. Theory and practice of counseling and psychotherapy. Cengage learning. 2012.
  42. Alilou MM, Yadegari N, Haghnazari F, Poursharifi H, Nosratabad TH. The effects of family cognitive-behavioral therapy in the reduction of anxiety in children with anxiety disorders. Biannual J Appl Counsel. 2013;1(3):19-34.
  43. Mohammad ZFA, Nadri F, Ahadi H, Rajabzadeh A, Kraskian A. Effectiveness of cognitive-behavioral therapy on social anxiety and blood glycemic control in children with type 1 diabetes mellitus. Psychol Achiev. 2016;23(2):91-112.
  44. Shahabizadeh F, Khaje Aminiyan F. The effectiveness of narrative therapy based on cognitive-behavioral perspective on anxiety of primary school female students. Knowledge Res Appl Psychol. 2018;19(1):70-80.
  45. Rahmanian Z, Mirzaian B, Hassanzadeh R. Effectiveness of cognitive-behavioral group therapy on social anxiety of female students. Daneshvar Med. 2020;19(5):47-56.
  46. Narimani M, Abolgasemi A, Reza Zadh H. The effects of cognitive-behavioral group therapy on life quality and academic performance of students with generalized social anxiety disorder. Biannual J Appl Counsel. 2012;1(2):31-50.
QR code:

Short Link:
Views: 37924

Downloads: 4905
Quick Access

Associations

Pharmacophore
ISSN: 2229-5402

Copyright © 2026 Pharmacophore. Authors retain copyright of their article if they are accepted for publication.
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.