TY  - JOUR
T1  - Effect of Stress on Hormone Levels in the Blood Serum of Rats with Alimentary Obesity
A1  - Vladimir Vladimirovich Shotaev
A1  - Karina Ruslanovna Doshkhokloeva
A1  - Petimat Hozh-Ahmedovna Vakhidova
A1  - Ruslan Aleksandrovich Dudkin
A1  - Daria Yurievna Kostiukova
A1  - Stella Muratovna Ionova
A1  - Marizhat Kamilovna Burzhunova
A1  - Antonina Viktorovna Tsybulina
JF  - Pharmacophore
JO  - Pharmacophore
SN  - 2229-5402
Y1  - 2024
VL  - 15
IS  - 3
DO  - 10.51847/kqAKevHg3e
SP  - 47
EP  - 52
N2  - Nowadays obesity is considered a complex chronic disease that poses a serious threat to health due to its associated cardiovascular and metabolic complications. One of the key regulators that can trigger the development of pathological processes in obesity is adipose tissue hormones – adipokines, among which leptin, adiponectin, and visfatin should be highlighted. To assess the degree of influence of a stable emotional stress state on the secretory activity of adipose tissue in the blood serum of obese rats, changes in the level of adipose tissue hormones - leptin, adiponectin, and visfatin were analyzed. It has been shown that a decrease in serum leptin levels in conditions of chronic stress can cause eating disorders, and the level of the hormone visfatin depends not only on the amount of adipose tissue. The results of the study suggest that chronic stress on the background of obesity accelerates the development of insulin resistance.
UR  - https://pharmacophorejournal.com/article/effect-of-stress-on-hormone-levels-in-the-blood-serum-of-rats-with-alimentary-obesity-rnxtsfnyzerrs8g
ER  -