TY  - JOUR
T1  - Hibiscus sabdariffa Leaf Extract Activates Molecular Gene Expressions of Insulin and GLP-I Receptor in Streptozotocin-Induced Rats
A1  - Basiru Olaitan Ajiboye
A1  - Courage Dele Famusiwa
A1  - Adetutu Omolola Ojelabi
A1  - Waliu Olalekan Akinola
A1  - Elijah Toluwase Adeyemi
A1  - Adedeji A. Adejumo
A1  - Olutunmise Victoria Owolabi
A1  - Temitope Olawale Jeje
A1  - Fisayo Abraham Bamisaye
A1  - Babatunji Emmanuel Oyinloye
A1  - Sara Vitalini
A1  - Marcello Iriti
JF  - Pharmacophore
JO  - Pharmacophore
SN  - 2229-5402
Y1  - 2024
VL  - 15
IS  - 5
DO  - 10.51847/xSFzqq25OY
SP  - 15
EP  - 26
N2  - This work investigated the therapeutic effects of flavonoid-rich extracts obtained from Hibiscus sabdariffa L. leaves in streptozotocin-induced diabetic rats. Their biochemical parameters such as redox stress biomarkers, anti-inflammatory levels, pancreatic histology, insulin concentration, lipase activity, purinergic enzyme activities, homeostasis model assessment of β-cells (HOMA-β), and homeostasis model assessment of insulin resistance (HOMA-IR) were assessed. Furthermore, the relative gene expressions of insulin receptors and GLP-1 were examined. H. sabdariffa extracts significantly (p
UR  - https://pharmacophorejournal.com/article/hibiscus-sabdariffa-leaf-extract-activate-molecular-gene-expressions-of-insulin-and-glp-i-receptor-i-yvpqjqguxwahau7
ER  -