%0 Journal Article
%T Linum Usitatissimum L. Protects Against Dyslipidemia and Oxidative Damage in Streptozotocin-Induced Diabetic Rats
%A Fatima Zohra Alachaher
%A Djamil Krouf
%A Zoheir Mellouk
%A Nawal Taleb-Dida
%J Pharmacophore
%@ 2229-5402
%D 2020
%V 11
%N 3
%P 130-140
%X Flaxseeds (Linum usitatissimum) (LU) are the richest source of α-linolenic acid and lignans. The present investigation aimed to assess the effect of Linum usitatissimum L. (LU) powder on experimental streptozotocin (STZ)-induced diabetes in Wistar rats. STZ was injected at a single dose of sixty mg/kg of body weight (BW) to induce diabetes mellitus. 20 diabetic rats were allocated into two groups and fed a casein diet supplemented or not with LU powder (1g/100g diet). The animals of the control group (n=10) were fed a standard diet. The animals were sacrificed after 56 days of the experiment and biochemical assays were carried out on plasma and tissue homogenates. Histological modifications were also witnessed in the liver, pancreas, and kidney. At d56, in LU treated vs untreated diabetic groups, glycemia and HBA1c levels were decreased significantly (p
%U https://pharmacophorejournal.com/article/linum-usitatissimum-l-protects-against-dyslipidemia-and-oxidative-damage-in-streptozotocin-induced-diabetic-rats