TY  - JOUR
T1  - Nephropathy in Adolescents with Type 1 Diabetes Mellitus: Systematic Review
A1  - Rawan Deham AlEdeilah
A1  - Ahmed Saad AlSulailm
A1  - Saad Mufadhi AlAnazi
A1  - Mohammed Fahad AlAnazi
A1  - Nawaf Fadel Naif AlEnazi
A1  - Rahaf Rahaf Muteb Saleh Alanazi Alanoud Shafyan Awadh Alanazi
A1  - Khulud Abdullah ALzahrani
A1  - Norah Mohsen Al Bogami
A1  - Reem Hassan Moafa
A1  - Mazyad Hamed AlMutairi
JF  - Pharmacophore
JO  - Pharmacophore
SN  - 2229-5402
Y1  - 2022
VL  - 13
IS  - 4
DO  - 10.51847/eC6QibkaX4
SP  - 135
EP  - 141
N2  - Diabetic nephropathy (DN) is an emerging public health and clinical issue linked to heart failure, ESRD, and other negative effects, including renal replacement therapy. A systematic search of five major databases, including PubMed, Web of Science, Science Direct, EBSCO, and Cochrane library, was conducted to comprise eligible literature for research. This systematic review studies the risk factors associated with the development of DN and albuminuria in adolescents suffering from T1DM. A total of 13 study articles with 1489 patients were included in this review. Hypertension in association with albuminuria was found in six studies, high mean HbA1c in association with DN was demonstrated in all the included studies, and dyslipidemia/ high total cholesterol level was reported in three studies. Hypertension, high HbA1C (poor glycemic control), dyslipidemia, high cholesterol levels, and high BMI indicating overweight or obesity are risk factors for the incidence of microalbuminuria and DN in adolescents with T1DM.
UR  - https://pharmacophorejournal.com/article/nephropathy-in-adolescents-with-type-1-diabetes-mellitus-systematic-review-dxotqoiwochpoc6
ER  -