%0 Journal Article
%T Phytochemical Assessment and Potential Pharmacological Activity of Moringa Oleifera Extract
%A Aziza Alisherovna Turakhanova
%A Fatima Khamzatovna Bidzhieva
%A Daria Vasilyevna Solovyeva
%A Deni Sayd-Magomedovich Berzigov
%A Arina Gamletovna Kelbisova
%A Anzhela Anzorovna Sokhova
%A Aza Bashirovna Dzeitova
%A Umiat Magomedovna Koymurzaeva
%J Pharmacophore
%@ 2229-5402
%D 2024
%V 15
%N 4
%R 10.51847/SQXx1aohWy
%P 46-53
%X The antioxidant activity of the extracts was determined by their ability to protect epinephrine hydrochloride from autooxidation. Extracts obtained from the herb and morphological parts of Moringa oleifera showed the greatest activity when extracted with an aqueous alcohol mixture with an alcohol content of 40%. Dry alcohol extract from the herb Moringa oleifera contains a bio-element complex, potentially possessing antioxidant activity: tannins (up to 30%), flavonoids (up to 5%), coumarins (up to 3.5%), phenol carbonic and oxycoric acids (up to 6%), amino acids (up to 2%), ascorbic acid, chlorophylls, carotenodes and 61 elements. The antioxidant activity of extracts (inactivation of radicals) is provided by biologically active substances of a phenolic nature (due to the presence of double bonds), ascorbic acid, and elements with variable valence, carotenoids, chlorophylls bind reactive oxygen species. Studies of anti-inflammatory activity (in acute and chronic inflammation) have determined the antiproliferative and phlogogenic effect of the dry herb extract, which is more pronounced than that of the comparison drug, acetylsalicylic acid. The dependence between the manifestation of antioxidant activity and the anti-inflammatory effect of Moringa oleifera extract of dry grass was revealed.
%U https://pharmacophorejournal.com/article/phytochemical-assessment-and-potential-pharmacological-activity-of-moringa-oleifera-extract-xyifurrfla6qzsm