%0 Journal Article
%T Preparation of a New Enterosorbent Bentorb and Determination of Its Toxicological Properties
%A Liana Araratovna Arakelyan
%A Polina Gennadievna Kamentseva
%A Aiza Delimkhanova Mashakova
%A Vitaliya Vitalievna Kolesnichenko
%A Inna Iurevna Karoli
%A Vladislav Vladimirovich Voropaev
%J Pharmacophore
%@ 2229-5402
%D 2024
%V 15
%N 2
%R 10.51847/d4HrIDWggY
%P 105-112
%X This article presents the results of several studies of the new Bentorb sorbent, which is produced from wine-making waste - adhesive deposits of yellow blood salt. It was found that oxygen, carbon, silicon, aluminum, iron, nitrogen, and magnesium occupy the largest percentage in the sorbent sample. Studies of the toxicological properties of Bentorb sorbent were carried out on laboratory animals. Studies of the acute toxicity of the Bentorb sorbent were conducted on 60 white mongrel rats weighing 237 ± 7 g. Experiments found that the general clinical condition of rats from all experimental and control groups did not change significantly, all animals remained alive. Studies of the chronic toxicity of Bentorb sorbent were conducted on 60 white mice and 40 Wistar rats weighing 185±12 g. During the study period, no significant differences in the general condition and survival of control and experimental animals were observed. The study of the effect of Bentorb sorbent on the function of the digestive tract was carried out on piglets 40-80 days old. The study of the effect of Bentorb sorbent on the function of the digestive tract was carried out on piglets 40-80 days old. The embryotoxic effect of Bentorb sorbent was studied on pregnant Wistar rats with an average body weight of 200-240 g. In addition, a study of body weights and some internal organs of laboratory animals, a control group, and an experimental one taking Bentorb sorbent was conducted.
%U https://pharmacophorejournal.com/article/preparation-of-a-new-enterosorbent-bentorb-and-determination-of-its-toxicological-properties-mgm8k50lj9iu0pz