TY  - JOUR
T1  - Primary Immune Deficiency Disease in Saudi Children: Systematic Review
A1  - Nazim Faisal Hamed Ahmed
A1  - Abrar Hamoud Mohammed Albalawi
A1  - Afrah Zaal Mohammed Albalawi
A1  - Tharaa Abdulkareem Alanazi
A1  - Sami Najeeb Shubat Alanazi
JF  - Pharmacophore
JO  - Pharmacophore
SN  - 2229-5402
Y1  - 2022
VL  - 13
IS  - 4
DO  - 10.51847/isksJQNQxO
SP  - 119
EP  - 124
N2  - The study aims to summarize current evidence regarding the primary immune deficiency disease in Saudi children. The PubMed database Information Services was utilized for article selection. In our review, we used all relevant articles related to our issue as well as unrelated publications. Other papers that were unrelated to this field were not considered. The data was extracted in a specified format, which the group members examined. Literature shows from the table it is clear that Combined immunodeficiencies were the most common (59.7%), followed by Phagocytic disorders (57.2%) then, predominantly antibody deficiencies (12.3%) among our PID patients. There was no difference in the frequency of B-cell and T-cell abnormalities. PID is not infrequent in Kuwait. Kuwaitis had a prevalence of 20.27/100,000, with a cumulative incidence of 24.96/100,000 Kuwaitis. The estimated frequency in Tunis was 4.3 per 100,000 people. Collaborative measures, such as the implementation of newborn screening, should be conducted to detect such instances early, enhance the quality of life, and avoid untimely deaths. The most prevalent were combined immunodeficiencies (59.7%), followed by phagocytic diseases (57.2%) then, predominantly antibody deficiencies (12.3%) among our PID patients. Collaborative measures, such as the implementation of newborn screening, should be conducted to detect such instances early, enhance the quality of life, and avoid untimely deaths. More systematic, multicenter, large-sample prospective studies with a larger sample size are necessary.
UR  - https://pharmacophorejournal.com/article/primary-immune-deficiency-disease-in-saudi-children-systematic-review-gs1dsecemgbrnfc
ER  -