%0 Journal Article %T Protective and Histological Effects of Kumquat ( Citrus japonica ) Extract in Rats Injected with Carbon Tetrachloride (CCl4) %A Lobna Saad Mohammed Abd Elmeged %A Khulud Mohammed Alshehri %J Pharmacophore %@ 2229-5402 %D 2024 %V 15 %N 2 %R 10.51847/Wo07IlXueK %P 43-53 %X Kumquat or Japanese orange, the smallest tree of the citrus family, grows and gives the best and largest production and the sweetest of fruits in warmer regions. The kumquat has protective importance and a great treat. Several vital metabolic processes, including the delivery and digestion of nutrients, are carried out by the liver., thus we focused on This investigation sought to determine the histological and protective impacts of Kumquat extract in rats given injections of carbon tetrachloride (CCl4). The experiment was conducted in a cage for animals. Before the experiment began, all of the rats were given a baseline diet for a week. The rats were then separated into 5 groups, each with 6 rats. The first group was fed a basal diet exclusively for 28 days as a control negative (C -ve) normal group of rats. The rats of the remaining groups (n = 24 rats) were given injections of Ccl4. The groups were split into four groups, with 3 groups receiving ethanol extracts of kumquats in various levels (150, 200, and 250 mg/kg), and one group serving as a control that had the illness but didn't follow the experimental diet. All hepatic rats given different diets exhibited substantial mean value declines as contrasted with the control (+) group, according to the data. As contrasted with the healthy group, group 5 had the best therapy for serum ALP to cause hepatopathy (normal rats). This research advised consuming kumquats, which may be had every day. %U https://pharmacophorejournal.com/article/protective-and-histological-effects-of-kumquat-citrus-japonica-extract-in-rats-injected-with-car-qzqgr1bejnf1svu