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  <front>
    <journal-meta>
      <journal-id journal-id-type="iso-abbrev">Pharmacophore</journal-id>
      <journal-id journal-id-type="publisher-id">pharmacophorejournal.com</journal-id>
      <journal-id journal-id-type="publisher-id">Pharmacophore</journal-id>
      <journal-title-group>
        <journal-title>Pharmacophore</journal-title>
      </journal-title-group>
      <issn pub-type="epub">2229-5402</issn>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">pharmacophorejournal.com-6789</article-id>
      <article-id pub-id-type="doi">10.51847/AH7qO6LMZD</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Original research</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Evolution of Esophageal Stricture Treatment by Use of Stents in Benign and Malignant Conditions</article-title>
      </title-group>
                    <contrib-group>
                      <contrib contrib-type="author">
              <name>
                <surname>Noor</surname>
                <given-names>Hassan</given-names>
              </name>
                              <xref rid="aff1" ref-type="aff">1</xref>
                              <xref rid="aff2" ref-type="aff">2</xref>
                                        </contrib>
                      <contrib contrib-type="author">
              <name>
                <surname>Sabău</surname>
                <given-names>Dan</given-names>
              </name>
                              <xref rid="aff1" ref-type="aff">1</xref>
                                        </contrib>
                      <contrib contrib-type="author">
              <name>
                <surname>Coțe</surname>
                <given-names>Adrian</given-names>
              </name>
                              <xref rid="aff3" ref-type="aff">3</xref>
                                                            <xref rid="cor1" ref-type="corresp" />
                          </contrib>
                      <contrib contrib-type="author">
              <name>
                <surname>Mihetiu</surname>
                <given-names>Alin Florin</given-names>
              </name>
                              <xref rid="aff1" ref-type="aff">1</xref>
                                        </contrib>
                      <contrib contrib-type="author">
              <name>
                <surname>Pirvut</surname>
                <given-names>Valentin</given-names>
              </name>
                              <xref rid="aff1" ref-type="aff">1</xref>
                                        </contrib>
                      <contrib contrib-type="author">
              <name>
                <surname>Mălinescu</surname>
                <given-names>Bogdan</given-names>
              </name>
                              <xref rid="aff4" ref-type="aff">4</xref>
                                        </contrib>
                      <contrib contrib-type="author">
              <name>
                <surname>Bratu</surname>
                <given-names>Dan Georgian</given-names>
              </name>
                              <xref rid="aff1" ref-type="aff">1</xref>
                                        </contrib>
                  </contrib-group>
                  <aff id="aff1">
            <label>1</label>Department of Surgical, Faculty of Medicine, “Lucian Blaga” University, Sibiu, Romania.
          </aff>
                  <aff id="aff2">
            <label>2</label>Hospital Medlife-Polisano, Sibiu, Romania.
          </aff>
                  <aff id="aff3">
            <label>3</label>Department of Surgical, Faculty of Medicine and Pharmacy, University of Oradea, Oradea, Romania.
          </aff>
                  <aff id="aff4">
            <label>4</label>Department of Legal Sciences, Faculty of Law, Romanian-American University, Bucharest, Romania.
          </aff>
                          <author-notes>
            <corresp id="cor1">
              <bold>Address for correspondence:</bold> Prof. Wael Abu Dayyih, Department of
              Pharmaceutical Chemistry, Faculty of Pharmacy, Mutah University, Al-Karak 61710, Jordan.
                              E-mail: <email xlink:href="adrian.cote@gmail.com">adrian.cote@gmail.com</email>
                          </corresp>
          </author-notes>
                    <pub-date pub-type="epub">
        <day>27</day>
        <month>02</month>
        <year>2024</year>
      </pub-date>
      <volume>15</volume>
      <issue>1</issue>
      <fpage>1</fpage>
      <lpage>5</lpage>
      <permissions>
        <copyright-statement>
          Copyright: &#x000a9; 2026 Pharmacophore
        </copyright-statement>
        <copyright-year>2026</copyright-year>
        <license>
          <ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/"
            specific-use="textmining" content-type="ccbyncsalicense">
            https://creativecommons.org/licenses/by-nc-sa/4.0/</ali:license_ref>
          <license-p>This is an open access journal, and articles are distributed under the terms of
            the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows
            others to remix, tweak, and build upon the work non-commercially, as long as appropriate
            credit is given and the new creations are licensed under the identical terms.</license-p>
        </license>
      </permissions>
      <abstract>
        <title>A<sc>BSTRACT</sc></title>
        <p>The esophagus is a muscular membranous organ that participates in the swallowing process by passing solid and liquid substrates from the pharynx into the stomach. The embryonic endoderm, mesoderm, and neural crest cells participate in the development of the esophagus. The pathology of the esophagus is very varied and surgical correction techniques require numerous improvements and refinements. The most common condition is Barret&amp;#39;s esophagus due to gastroesophageal reflux, but strictures can also occur either from neoplastic causes or from chemical burns. Studying the anatomy and physiology of the esophagus is essential for both internal medicine and surgical approaches. The treatment of esophageal strictures in recent times is done with esophageal stents. These are made of a variety of materials including metal, polymer, or biodegradable. Clinical results are very good but complications are quite common. The first attempt at stenting was made in the mid-19th century using an ivory tube. In the case of ingestion of caustic substances dilation and stenting have very good results. Immediate and late complications are multiple and can range from pain to failure of the stent to expand completely.</p>
      </abstract>
      <kwd-group>
                <kwd>Esophagus</kwd>
                <kwd>Esophagus strictures</kwd>
                <kwd>Endoscopic procedure</kwd>
                <kwd>Esophageal stents</kwd>
              </kwd-group>
    </article-meta>
  </front>
</article>