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  <front>
    <journal-meta>
      <journal-id journal-id-type="iso-abbrev">Pharmacophore</journal-id>
      <journal-id journal-id-type="publisher-id">pharmacophorejournal.com</journal-id>
      <journal-id journal-id-type="publisher-id">Pharmacophore</journal-id>
      <journal-title-group>
        <journal-title>Pharmacophore</journal-title>
      </journal-title-group>
      <issn pub-type="epub">2229-5402</issn>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">pharmacophorejournal.com-6821</article-id>
      <article-id pub-id-type="doi">10.51847/Ef8mXZoE1J</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Original research</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Innovative Vacuum Technology for Cataract Treatment - Effect on the Condition of Cornea of Eye</article-title>
      </title-group>
                    <contrib-group>
                      <contrib contrib-type="author">
              <name>
                <surname>Beshieva</surname>
                <given-names>Kamila Bekhanovna</given-names>
              </name>
                              <xref rid="aff1" ref-type="aff">1</xref>
                                        </contrib>
                      <contrib contrib-type="author">
              <name>
                <surname>Albukaeva</surname>
                <given-names>Rayan Ruslanovna</given-names>
              </name>
                              <xref rid="aff1" ref-type="aff">1</xref>
                                        </contrib>
                      <contrib contrib-type="author">
              <name>
                <surname>Magomadova</surname>
                <given-names>Guri Khasanovna</given-names>
              </name>
                              <xref rid="aff1" ref-type="aff">1</xref>
                                        </contrib>
                      <contrib contrib-type="author">
              <name>
                <surname>Musukova</surname>
                <given-names>Saada Khasanovna</given-names>
              </name>
                              <xref rid="aff2" ref-type="aff">2</xref>
                                        </contrib>
                      <contrib contrib-type="author">
              <name>
                <surname>Gudaeva</surname>
                <given-names>Indira Khavazhievna</given-names>
              </name>
                              <xref rid="aff1" ref-type="aff">1</xref>
                                        </contrib>
                      <contrib contrib-type="author">
              <name>
                <surname>Madagova</surname>
                <given-names>Dana Magomedovna</given-names>
              </name>
                              <xref rid="aff1" ref-type="aff">1</xref>
                                        </contrib>
                      <contrib contrib-type="author">
              <name>
                <surname>Musaeva</surname>
                <given-names>Aminat Astamirovna</given-names>
              </name>
                              <xref rid="aff1" ref-type="aff">1</xref>
                                        </contrib>
                      <contrib contrib-type="author">
              <name>
                <surname>Mezhidova</surname>
                <given-names>Raisa Hamsurbekovna</given-names>
              </name>
                              <xref rid="aff1" ref-type="aff">1</xref>
                                                            <xref rid="cor1" ref-type="corresp" />
                          </contrib>
                  </contrib-group>
                  <aff id="aff1">
            <label>1</label>Department of Therapy, Faculty of Medicine, Medical Institute, Chechen State University named after A. A. Kadyrov, Grozny, Republic of Chechnya, Russia.
          </aff>
                  <aff id="aff2">
            <label>2</label>Department of Therapy, Faculty of Medicine, Kabardino-Balkarian State University named after H.M. Berbekov, Nalchik, Republic of Kabardino-Balkaria, Russia.
          </aff>
                          <author-notes>
            <corresp id="cor1">
              <bold>Address for correspondence:</bold> Prof. Wael Abu Dayyih, Department of
              Pharmaceutical Chemistry, Faculty of Pharmacy, Mutah University, Al-Karak 61710, Jordan.
                              E-mail: <email xlink:href="bucky99@ya.ru">bucky99@ya.ru</email>
                          </corresp>
          </author-notes>
                    <pub-date pub-type="epub">
        <day>28</day>
        <month>08</month>
        <year>2024</year>
      </pub-date>
      <volume>15</volume>
      <issue>4</issue>
      <fpage>15</fpage>
      <lpage>19</lpage>
      <permissions>
        <copyright-statement>
          Copyright: &#x000a9; 2026 Pharmacophore
        </copyright-statement>
        <copyright-year>2026</copyright-year>
        <license>
          <ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/"
            specific-use="textmining" content-type="ccbyncsalicense">
            https://creativecommons.org/licenses/by-nc-sa/4.0/</ali:license_ref>
          <license-p>This is an open access journal, and articles are distributed under the terms of
            the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows
            others to remix, tweak, and build upon the work non-commercially, as long as appropriate
            credit is given and the new creations are licensed under the identical terms.</license-p>
        </license>
      </permissions>
      <abstract>
        <title>A<sc>BSTRACT</sc></title>
        <p>The problem of cataract prevalence makes it necessary to develop innovative technologies for eye microsurgery. An innovative hydrodynamic scheme has been developed by a team of researchers. Its essence lies in the fact that when the vacuum level in the aspiration line reaches critical figures and remains at this level for a specified time, the system recognizes this state as occlusion and smoothly reduces the vacuum to a preset value while maintaining occlusion. The purpose of this scientific study is to study morphological changes in the cornea of rabbits&amp;#39; eyes after experimental modeling of a post-occlusion wave using a new hydrodynamic scheme of a phaco-emulsifier. The study was conducted on 32 eyes of 16 white laboratory rabbits, using traditional technology and an innovative hydrodynamic scheme, as well as needles of various diameters. The pieces of the cornea were carefully examined using a light microscope. The least damage to the cornea of the eye was found in the fourth group of rabbits, where an innovative hydrodynamic scheme was used in combination with a thin needle d = 0.9 mm.</p>
      </abstract>
      <kwd-group>
                <kwd>Ophthalmology</kwd>
                <kwd>Cataract</kwd>
                <kwd>Occlusion</kwd>
                <kwd>Hydrodynamic scheme</kwd>
                <kwd>Phaco-emulsifier</kwd>
              </kwd-group>
    </article-meta>
  </front>
</article>