With dietary supplements being important in the prevention and treatment of common diseases, Russian researchers focus on using local plants and aquatic animals. A new dietary supplement containing marsh cinquefoil extract, burdock root extract, fish cartilaginous tissues, and cephalopods was developed. The present study examines the potency of the ingredients, formulation, the qualitative and quantitative composition of the dietary product, the manufacturing process, as well ands the laboratory testing (organoleptic, physico-chemical, microbiological, toxicological) of the finished product. The shelf life of the product is 2 years when stored at 4-12°С in a dark place. The recipe and technology of the developed additive were tested under production conditions at the enterprises of NPO Biolit (Tomsk). The functional properties of the supplement are confirmed by the results of clinical studies for rheumatoid arthritis. Prescription leads to a halving of the severity of clinical and laboratory symptoms in 80% of patients. A decrease in pain and the absence of internal stiffness were established, and positive dynamics in assessing the quality of life were established: improved mood, decreased frequency of headaches.