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  <front>
    <journal-meta>
      <journal-id journal-id-type="iso-abbrev">Pharmacophore</journal-id>
      <journal-id journal-id-type="publisher-id">pharmacophorejournal.com</journal-id>
      <journal-id journal-id-type="publisher-id">Pharmacophore</journal-id>
      <journal-title-group>
        <journal-title>Pharmacophore</journal-title>
      </journal-title-group>
      <issn pub-type="epub">2229-5402</issn>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">pharmacophorejournal.com-6829</article-id>
      <article-id pub-id-type="doi">10.51847/Whuu5OqduM</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Original research</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>The Effect of Low-Intensity Electromagnetic Radiation of Extremely High Frequency on Heart Rate Variability</article-title>
      </title-group>
                    <contrib-group>
                      <contrib contrib-type="author">
              <name>
                <surname>Tanasov</surname>
                <given-names>Egor Igorevich</given-names>
              </name>
                              <xref rid="aff1" ref-type="aff">1</xref>
                                        </contrib>
                      <contrib contrib-type="author">
              <name>
                <surname>Polunina</surname>
                <given-names>Elizaveta Romanovna</given-names>
              </name>
                              <xref rid="aff1" ref-type="aff">1</xref>
                                        </contrib>
                      <contrib contrib-type="author">
              <name>
                <surname>Shapovalov</surname>
                <given-names>Vladislav Dmitrievich</given-names>
              </name>
                              <xref rid="aff1" ref-type="aff">1</xref>
                                        </contrib>
                      <contrib contrib-type="author">
              <name>
                <surname>Revin</surname>
                <given-names>Danil Vladimirovich</given-names>
              </name>
                              <xref rid="aff1" ref-type="aff">1</xref>
                                        </contrib>
                      <contrib contrib-type="author">
              <name>
                <surname>Mikhaelyan</surname>
                <given-names>David Armenovich</given-names>
              </name>
                              <xref rid="aff1" ref-type="aff">1</xref>
                                        </contrib>
                      <contrib contrib-type="author">
              <name>
                <surname>Mikhaelyan</surname>
                <given-names>Eduard Armenovich</given-names>
              </name>
                              <xref rid="aff1" ref-type="aff">1</xref>
                                        </contrib>
                      <contrib contrib-type="author">
              <name>
                <surname>Malsagov</surname>
                <given-names>Solehadin Ibragimovich</given-names>
              </name>
                              <xref rid="aff1" ref-type="aff">1</xref>
                                        </contrib>
                      <contrib contrib-type="author">
              <name>
                <surname>Zarmaeva</surname>
                <given-names>Aminat Kazbekovna</given-names>
              </name>
                              <xref rid="aff2" ref-type="aff">2</xref>
                                                            <xref rid="cor1" ref-type="corresp" />
                          </contrib>
                  </contrib-group>
                  <aff id="aff1">
            <label>1</label>Department of Therapy, Faculty of Medicine of Stavropol State Medical University, Stavropol, Russia.
          </aff>
                  <aff id="aff2">
            <label>2</label>Department of Therapy, Faculty of Medicine, Medical Institute, Chechen State University named after A. A. Kadyrov, Grozny, Republic of Chechnya, Russia.
          </aff>
                          <author-notes>
            <corresp id="cor1">
              <bold>Address for correspondence:</bold> Prof. Wael Abu Dayyih, Department of
              Pharmaceutical Chemistry, Faculty of Pharmacy, Mutah University, Al-Karak 61710, Jordan.
                              E-mail: <email xlink:href="bucky99@ya.ru">bucky99@ya.ru</email>
                          </corresp>
          </author-notes>
                    <pub-date pub-type="epub">
        <day>20</day>
        <month>07</month>
        <year>2024</year>
      </pub-date>
      <volume>15</volume>
      <issue>4</issue>
      <fpage>39</fpage>
      <lpage>45</lpage>
      <permissions>
        <copyright-statement>
          Copyright: &#x000a9; 2026 Pharmacophore
        </copyright-statement>
        <copyright-year>2026</copyright-year>
        <license>
          <ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/"
            specific-use="textmining" content-type="ccbyncsalicense">
            https://creativecommons.org/licenses/by-nc-sa/4.0/</ali:license_ref>
          <license-p>This is an open access journal, and articles are distributed under the terms of
            the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows
            others to remix, tweak, and build upon the work non-commercially, as long as appropriate
            credit is given and the new creations are licensed under the identical terms.</license-p>
        </license>
      </permissions>
      <abstract>
        <title>A<sc>BSTRACT</sc></title>
        <p>Due to its high biological efficiency, extremely high-frequency electromagnetic radiation is used in medical practice to treat a wide range of diseases, including the cardiovascular system. The purpose of this work was to study the indicators of heart rate variability during the recovery period after a bicycle ergometric test under the conditions of preventive exposure to low-intensity electromagnetic radiation of extremely high frequency. The study involved 120 young girls in the intermenstrual period. The girls in the experimental group were exposed to 30 minutes of low-intensity electromagnetic radiation of extremely high frequency for 10 days. Then all the subjects took part in bicycle ergometric training. In the experimental group, a decrease in the stress index by 36%, and an increase in the power of the spectrum by 64% was noted, which indicates the activation of the parasympathetic division of the vegetative-vascular nervous system and normalization of vegetative effects on the heart. In the experimental group, compared with the control group, there was a less pronounced change in the considered parameters of cardiac activity.</p>
      </abstract>
      <kwd-group>
                <kwd>Heart rate</kwd>
                <kwd>Electromagnetic radiation</kwd>
                <kwd>Extremely high frequency</kwd>
                <kwd>Sympathoadrenal system</kwd>
                <kwd>Physical activity</kwd>
              </kwd-group>
    </article-meta>
  </front>
</article>