Dyshormonal dysplasia of the mammary glands is the most common pathology that practitioners encounter. The interest of clinicians in these processes is related to several circumstances. On the one hand, effective treatment that relieves symptoms guarantees quality of life. On the other hand, mastopathy is a risk factor for the further development of a malignant tumor. Therefore, timely correction of dysplasia can be considered an option for the primary prevention of breast cancer. Choosing an adequate management strategy for such patients from the variety of existing dosage forms is the key to the success of treatment. The article is devoted to the consideration of pharmacological effects and the main molecular mechanisms of action in phyto-preparations based on Chlorophytum comosum. Taking into account its good tolerability, high efficacy in various clinical situations, and ease of use, we can confidently say that Chlorophytum comosum extract continues to occupy the position of one of the leaders of modern conservative treatment of diffuse pathology of the breast.