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  <front>
    <journal-meta>
      <journal-id journal-id-type="iso-abbrev">Pharmacophore</journal-id>
      <journal-id journal-id-type="publisher-id">pharmacophorejournal.com</journal-id>
      <journal-id journal-id-type="publisher-id">Pharmacophore</journal-id>
      <journal-title-group>
        <journal-title>Pharmacophore</journal-title>
      </journal-title-group>
      <issn pub-type="epub">2229-5402</issn>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">pharmacophorejournal.com-6787</article-id>
      <article-id pub-id-type="doi">10.51847/fgNnRx4qc2</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Original research</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Common Scaffolds in Tissue Engineering for Bone Tissue Regeneration: A Review Article</article-title>
      </title-group>
                    <contrib-group>
                      <contrib contrib-type="author">
              <name>
                <surname>Hozan</surname>
                <given-names>Călin Tudor</given-names>
              </name>
                              <xref rid="aff1" ref-type="aff">1</xref>
                              <xref rid="aff2" ref-type="aff">2</xref>
                                        </contrib>
                      <contrib contrib-type="author">
              <name>
                <surname>Coțe</surname>
                <given-names>Adrian</given-names>
              </name>
                              <xref rid="aff1" ref-type="aff">1</xref>
                              <xref rid="aff2" ref-type="aff">2</xref>
                                                            <xref rid="cor1" ref-type="corresp" />
                          </contrib>
                      <contrib contrib-type="author">
              <name>
                <surname>Bulzan</surname>
                <given-names>Mădălin</given-names>
              </name>
                              <xref rid="aff1" ref-type="aff">1</xref>
                              <xref rid="aff2" ref-type="aff">2</xref>
                                        </contrib>
                      <contrib contrib-type="author">
              <name>
                <surname>Szilagy</surname>
                <given-names>Gheorghe</given-names>
              </name>
                              <xref rid="aff1" ref-type="aff">1</xref>
                              <xref rid="aff2" ref-type="aff">2</xref>
                                        </contrib>
                  </contrib-group>
                  <aff id="aff1">
            <label>1</label>Department of Surgical Discipline, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania.
          </aff>
                  <aff id="aff2">
            <label>2</label>County Clinical Emergency Hospital of Oradea, 410087 Oradea, Romania.
          </aff>
                          <author-notes>
            <corresp id="cor1">
              <bold>Address for correspondence:</bold> Prof. Wael Abu Dayyih, Department of
              Pharmaceutical Chemistry, Faculty of Pharmacy, Mutah University, Al-Karak 61710, Jordan.
                          </corresp>
          </author-notes>
                    <pub-date pub-type="epub">
        <day>16</day>
        <month>01</month>
        <year>2024</year>
      </pub-date>
      <volume>14</volume>
      <issue>6</issue>
      <fpage>46</fpage>
      <lpage>51</lpage>
      <permissions>
        <copyright-statement>
          Copyright: &#x000a9; 2026 Pharmacophore
        </copyright-statement>
        <copyright-year>2026</copyright-year>
        <license>
          <ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/"
            specific-use="textmining" content-type="ccbyncsalicense">
            https://creativecommons.org/licenses/by-nc-sa/4.0/</ali:license_ref>
          <license-p>This is an open access journal, and articles are distributed under the terms of
            the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows
            others to remix, tweak, and build upon the work non-commercially, as long as appropriate
            credit is given and the new creations are licensed under the identical terms.</license-p>
        </license>
      </permissions>
      <abstract>
        <title>A<sc>BSTRACT</sc></title>
        <p>Regenerative medicine offers a new solution by cell therapy and tissue engineering methods to improve irreparable bone damage. Engineered structures help to accelerate the natural recovery of the tissue because in some bone injuries, the lost tissue is extensive and it is not possible to recover naturally. This article provides an overview of common scaffolds in tissue engineering for bone tissue regeneration. Because bone is a hard and inflexible tissue, therefore, biological materials that are hard like bone should be used for scaffold design. From this category of materials, we can mention bioactive glasses, which when these glasses are placed in the simulated environment of the body, form a crystal layer of hydroxyapatite in contact with the body&amp;#39;s physiological fluid. Choosing the right manufacturing method depends on the desired tissue structure. Considering the vital role of scaffolds in tissue engineering, several methods have been used to design and build good scaffolds for tissue engineering. Electrospinning is a common method for making scaffolding. In this technique, by changing the conditions, fibers from several microns to several nanometers can be created. Because the area ratio to the regional volume of the fibers obtained from electrospinning is high, this characteristic increases the connection and proliferation of cells on the scaffold. Therefore, the electrospun scaffold, which is a combination of bioactive glass and polymer, can provide the basis for the treatment of bone diseases.</p>
      </abstract>
      <kwd-group>
                <kwd>Scaffolds</kwd>
                <kwd>Tissue engineering</kwd>
                <kwd>Bone tissue</kwd>
                <kwd>Regeneration</kwd>
              </kwd-group>
    </article-meta>
  </front>
</article>