Introduction: Traditional herbs and drugs are the current choices of people in most areas where herbs are commonly being prescribed and used for the management of diseases. The current scenario of undertaking Ayurveda medications and herbs as a potent cure for many diseases is growing phenomenally. In this paper, we have presented a detailed analysis of a Himalayan Herb Selinum vaginatum, which is a good source and a potential treatment for curing many diseases. The potential of this herb is not much explored scientifically. It is found in the regions of Northern Himalayas alongside the states like Himachal Pradesh, Kashmir, Uttarakhand, high altitude regions China mainland (Himalayan region) – Kailash Mountain region, Pakistan, etc. Objectives: The main objective of the paper is to get detailed information about the taxonomical classification of species, traditional uses, pharmacological actions, and chemical composition of Selinum vaginatum. Material and Methods: The review was performed to gain detailed knowledge of Selinum vaginatum. The review was carried out using search engines to investigate tribal uses, pharmacological actions, and pharmacognostic characteristics. The data collected from multiple platforms were used in this research. Result: The roots of the plant have been used traditionally and show pharmacological activities like anti-fungal, anti-convulsion action, seed germination inhibition effects, sedative, analgesic and hypotensive actions, antioxidant activity, anti-epileptic and anti-hysteria effect, etc. The key constituents reported in the plant roots are Selenidin, Angelicin, Oroselol, alpha-pinene, camphene, elemol, limonene, 3, 5-nonadiyne, sesquiterpenoids (valerenic acids), phenol (chlorogenic acid), valeriananoids, essential oils, vaginidin, angelicin, selinidin, orosenol, and selinone. Conclusions: The information documented in this paper will be helpful for medicinal, commercial, and industrial uses. It will help grow information about this Himalayan herb and its unexplored therapeutic potentials can be tested pharmacologically. A lot of information about the tribal uses is also shared in this paper, which will direct the interest of researchers over this plant and test the activities of the essential oil and the components of Selinum vaginatum in vitro and in vivo. The analysis of the extracts from the plant must be well researched for pharmacologically active constituents to find the active constituents responsible for therapeutic benefits.