Pharmacophore an International Research Journal
Pergularia daemia is a perennial herb that grows along the roadsides of tropical and subtropical regions. The aim of the present study was to investigate the antimicrobial activity of ethanolic, methanolic and acetone extracts of Pergularia daemia leaves and roots against some pathogenic microorganisms such as Enterococcus faecalis, Bacillus anthracis and Aspergillus fumigates. In ayurveda the aerial parts of the plant are reported to have antifertility, antidiabetic, hepatoprotective activity, cardiovascular effect, antibacterial activity, antiseptic, antivenin, emmanagogue, emetic, expectorant etc. In this study it was found that methanolic extract of the leaves of Pergularia daemia showed maximum antimicrobial activity with increased zone of inhibition against Enterococcus faecalis than that of tetracycline and less activity against Bacillus anthracis and no antifungal activity against Aspergillus fumigates and the roots showed less inhibitory activity against Enterococcus faecalis and Bacillus anthracis and no antifungal activity was observed.
