TY  - JOUR
T1  - IN VITRO ANTIOXIDANT ACTIVITY OF NOVEL 4-HYDROXY-1-METHYL-3-(3-SUBSTITUTED)-4,5-DIHYDROISOXAZOL-5-YL)QUINOLIN-2(1H)-ONE DERIVATIVES
A1  - Arunadevi Parlapalli and Sarangapani Manda
JF  - Pharmacophore
JO  - Pharmacophore
SN  - 2229-5402
Y1  - 2015
VL  - 6
IS  - 5
SP  - 243
EP  - 248
N2  - A series of novel 4-Hydroxy-1-methyl-3-(3-substituted)-4,5-dihydroisoxazol-5-yl)quinolin-2(1H)-one derivatives were synthesized from chalcones (α, β-unsaturated compounds) well known compounds to exhibit antioxidant activities. All the synthesized compounds were characterized by spectral and analytical data and were evaluated for antioxidant activity by DPPH method using standard Ascorbic acid. All the compounds are known to exhibit antioxidant activity. Among them, compound (5f) exhibited the IC50 = 7.2 μM, standard (IC50 = 5.85 μM)
UR  - https://pharmacophorejournal.com/article/in-vitro-antioxidant-activity-of-novel-4-hydroxy-1-methyl-3-3-substituted-45-dihydroisoxazol-5-ylquinolin-21h-one-derivatives
ER  -