%0 Journal Article
%T In Vitro Study of The Antimicrobial Effect of Synthesized Copolymer Compounds ‎Against Staphylococcus Aureus and Escherichia Coli Strains
%A EL Korso Fatiha Narimene
%A Sebba Fatima Zohra
%A Rechache Mustapha
%J Pharmacophore
%@ 2229-5402
%D 2019
%V 10
%N 3
%P 82-88
%X The newly synthesized antimicrobial copolymers i.e. [poly N-vinylpyrrolidone -block- poly ε-caprolactone -ɷ-hydroxyethylmethacrylate] (KFB), [(poly N-vinylpyrrolidone -block- poly ε-caprolactone -ɷ-hydroxyethylmethacrylate) -graft- poly-4-Vinylpyridine] (KFC)  and   [(poly N-vinylpyrrolidone -block- poly ε-caprolactone -ɷ-hydroxyethylmethacrylate) -graft- poly-4-Vinylpyridine octyl bromide] (KFCQ), were tested in vitro, using diffusion disc method (MDD) against two microbial strains: gram-positive bacteria Staphylococcus aureus ATCC 25923 (S. aureus) and gram-negative bacteria Escherichia coli ATCC 25922 (E. coli). Good antibacterial activities were observed for all tested copolymers. It was demonstrated that gram-positive bacteria were more sensitive than gram-negatives, and KFCQ agent was more active than KFB and KFC‎‎.
%U https://pharmacophorejournal.com/article/in-vitro-study-of-the-antimicrobial-effect-of-synthesized-copolymer-compounds-against-staphylococcus-aureus-and-escherichia-coli-strains