TY  - JOUR
T1  - In Vitro Study of The Antimicrobial Effect of Synthesized Copolymer Compounds ‎Against Staphylococcus Aureus and Escherichia Coli Strains
A1  - EL Korso Fatiha Narimene
A1  - Sebba Fatima Zohra
A1  - Rechache Mustapha
JF  - Pharmacophore
JO  - Pharmacophore
SN  - 2229-5402
Y1  - 2019
VL  - 10
IS  - 3
SP  - 82
EP  - 88
N2  - The newly synthesized antimicrobial copolymers i.e. [poly N-vinylpyrrolidone -block- poly ε-caprolactone -ɷ-hydroxyethylmethacrylate] (KFB), [(poly N-vinylpyrrolidone -block- poly ε-caprolactone -ɷ-hydroxyethylmethacrylate) -graft- poly-4-Vinylpyridine] (KFC)  and   [(poly N-vinylpyrrolidone -block- poly ε-caprolactone -ɷ-hydroxyethylmethacrylate) -graft- poly-4-Vinylpyridine octyl bromide] (KFCQ), were tested in vitro, using diffusion disc method (MDD) against two microbial strains: gram-positive bacteria Staphylococcus aureus ATCC 25923 (S. aureus) and gram-negative bacteria Escherichia coli ATCC 25922 (E. coli). Good antibacterial activities were observed for all tested copolymers. It was demonstrated that gram-positive bacteria were more sensitive than gram-negatives, and KFCQ agent was more active than KFB and KFC‎‎.
UR  - https://pharmacophorejournal.com/article/in-vitro-study-of-the-antimicrobial-effect-of-synthesized-copolymer-compounds-against-staphylococcus-aureus-and-escherichia-coli-strains
ER  -