Luk (Laccifer lacca) is one of the most valuable gifts of Nature to man. It is also unique material in as much as it is the only resin of animal origin, being actually the secretion of a tiny insect, Laccifer lacca. Almost all physicians mentioned the medicinal properties and its therapeutic uses in their books and treatise, so many studies conducted for anti-obesity, anti-hyperlipidemic effect. But most of its action still not scientific validated. This drug is famous among unani practitioner as an anti-obesity agent and for its well-known effect on the hepatobiliary system also. So many Unani compound drugs formulations are available in the market and having chief ingredients as Luk and widely used in liver disorders and obesity. Apart of its medicinal use it is also used in various industries in wood finishing, printing ink, electrical industry, cosmetic and printing industry etc.