TY  - JOUR
T1  - QSAR AND DOCKING STUDIES OF CHLORPROPAMIDE DERIVATES
A1  - Teodora E. Harsa
A1  - Alexandra M. Harsa and Mircea V. Diudea
JF  - Pharmacophore
JO  - Pharmacophore
SN  - 2229-5402
Y1  - 2015
VL  - 6
IS  - 5
SP  - 208
EP  - 219
N2  - A study of 40 chlorpropamide derivatives, QSAR (Quantitative Structure Activity Relationship) and molecular docking approaches were applied to explore the structural requisites of chlorpropamide derivatives for CYTOCHROME P450 2C9 inhibitory activity. A set of forty chlorpropamide, was modeled, within the hypermolecule strategy; the predicted activity was LD50 and prediction was done on similarity clusters with the leaders chosen as the best docked ligands on the CYTOCHROME P450 2C9.
UR  - https://pharmacophorejournal.com/article/qsar-and-docking-studies-of-chlorpropamide-derivates
ER  -