A Review: Evaluation of the Factors Associated with Mortality after Primary PCI in an Iranian Population Download PDF

Background: Percutaneous coronary intervention (PCI) is considered the first treatment for early reperfusion in patients presenting with ST‐elevation myocardial infarction (STEMI). Yet, mortality rate after depends on various factors, like time-to-treatment, age, female sex, comorbidities, and clinical factors. Unlike significant decrease in CVD-related mortality rate in developed countries, it is still a serious public health threat in Iran. Objectives: The present study aimed to determine the factors affecting mortality after PCI in an Iranian population. Patients and Methods: The present cross-sectional study evaluated 89 patients with ST elevation MI (STEMI), candidate of Primary PCI in Emergency Department (ED) of Bu Ali hospital from April 2014 to May 2015. PCI was performed by an interventionalist; the cases with involvement of other vessels underwent staged PCI. Primary outcome in this study was mortality rate. Results: Type of the involved vessel was LAD in 54 patients (60.7%), RCA in 24 patients (27.0%), and LCX in 10 patients (11.2%). One vessel was involved in 9 patients (10.1%), two-vessel disease in 32 patients (36.0%), and three-vessel disease in 48 patients (53.9%). Mean EF was 43.98±9.85. The mortality rate was 4.5% (4 cases). The type and number of vessel involved, time to PCI, sex, and mean age were not (P>0.05), but mean EF was associated with mortality (P<0.001). Conclusion: The results of the present study shows that mean EF was found as the only factor associated with mortality, which necessitates that cardiologists pay greater attention to underlying cardiac status of patients with STEMI undergoing primary PCI.