An Overview of Kawasaki Disease Diagnosis and Management Approach Download PDF

AN OVERVIEW OF KAWASAKI DISEASE DIAGNOSIS AND MANAGEMENT APPROACH: LITERATURE REVIEW

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ABSTRACT

Background: Kawasaki disease (KD) is a febrile vasculitis disorder that is considered a life-threatening disease if left untreated. It is the most common cause of acquired cardiac diseases in pediatric patients in developed countries. Several debates have been discussed in the literature regarding diagnosing and treating cases of KD. Objective: To review the published literature that discussed KD's diagnosis and management to provide adequate coverage of the important aspects of KD. Conclusion: There is no specific diagnostic test for proper KD diagnosis. Therefore, the clinical features and laboratory findings should be combined to reach the diagnosis. Regarding management, combined Intravenous Immunoglobulins (IVIG) with aspirin is the recommended treatment for acute KD. However, corticosteroids are the recommended alternatives in treating severe KD in cases of IVIG resistance. Regarding the proper regimens of the different options, the proper dosage and duration vary from region to region and institution to institution.