The occurrence of anesthetic complications postoperatively is not unique. However, some anatomical and physiological change takes place after surgical procedures. Managing surgical patients remain challenging in different aspects and stages of hospital management. Morbidity and mortality that occurs postoperatively under incorrect dosing and administration are common for anesthesiologists injecting up to half a million medication throughout their profession. The expectancy and chances of committing errors are unpredictable and tragic. This review will guide anesthesiologists to modify new clinical skills that will aid their evaluation upon dealing with anesthetic complications. This literature review aims to examine and discuss the most undesirable complications categories and mortality rates after anesthetics administration. This review was obtained using an electronic-based search engine along with Google Scholar and PubMed. Anesthesiologists need to describe the complications in a categorized form, to clarify the anesthetics hazards as clear as possible. This will result in a better outcome for any at risk patients and make the intervention much quicker and precise.