Pharmacophore an International Research Journal
Capparis decidua Edgew (Forssk.) belongs to family Capparidaceae, the common name of this plant is Kirar. Capparis decidua Edgew (CdE) therapeutically active plant and successfully used in medicine. This study aimed to assess the antibacterial activity of methanol extract of CdE against four microorganisms two gram-positive (Staphylococcus aureus and Bacillus cereus) and two-gram negative (Salmonella typhi and Escherichia coli). The antibacterial activity of Capparis decidua Edgew leaves was assessed by the disc diffusion method. Antibiotics Cefixime (5mcg), Ceftriaxone (30mcg), Ciprofloxacin (5mcg), and Co-amoxiclav (30mcg) were used to compare the results of methanol extract of CdE that exhibit good antibacterial activity against all three microorganisms except one i.e S aureus. The results of Zone of inhibition of Methanol extract of Capparis decidua Edgew high against B cereus (21.21±1.2) and this activity comparable with Ceftriaxone (21.21± 0.45). The results have shown the MICs of methanol extract Capparis decidua Edgew were recorded high against gram-positive S. aureus 1.21±3.1mg/ml and gram-negative E coli 1.08 ± 5.81mg/ml. In conclusion, CdE exhibit profound antibacterial activity against microbes.
