This study aimed effectiveness of schema therapy on general consistency and quality of life in patients with SCI. Disabilities including spinal cord injury is reaching influence on the quality of life of patients with spinal cord injury patients with life and creates many problems. Therefore, 30 patients with available sampling from among persons with disabilities of SCI dynamic (under the auspices of the well-being of the province) have the lowest scores in the pretest questionnaire consistent and quality of life achieved, they were selected and then randomly simple Measuring Instruments Bell Adjustment Questionnaire (1961) and the short form quality of life questionnaire (1996) were the participants of the pre and post-test questionnaires. By testing hypotheses (MANCOVA) were tested. The results show that schema therapy on quality of life, improve public Compatibility significant effectiveness. It is concluded that schema therapy in the treatment of mental disorders can be disabled with SCI have a positive effect.