Pharmacophore an International Research Journal
Nasal colonization with community acquired methicillin resistant Staphylococcus aureus (CA-MRSA) is being increasingly reported, especially in places where in school children are in close contact and in reduced hygiene. Present study was carried out to find out the capsular typing of Staphylococcus aureus (S. aureus) coagulase positive (CoPS) in school children in few Districts in Tanga region, Tanzania. Total 1574 (784 from boys and 790 from girls) nasal swabs collected were subjected to standard bacteriological culture. S. aureus isolates were identified by mannitol fermentation, coagulase positivity. Antimicrobial susceptibility test was performed on muller-hinton agar (MHA) by modified Kirby-Bauer disc diffusion method with methicillin antibiotic. There was a high rate of S. aureus nasal colonization in boys (50.25%) and girls (51.01%) in the 5-15 year age group. An alarming rate of incidence of MRSA in boys (32.39) and girls (30.37) of community acquired methicillin resistant S. aureus nasal colonization in the community. Isolates resistant to methicillin was resistant to penicillin. In our findings the predominant capsular type in the region was type-8, it was 49.18% and T5 192 (29.05%) and for non T5/T8 200 (25.09%) for (CoPS) S. aureus and T8 for 261 (52.83%), T5 was 113 (22.87%) and non T5/T8 was 120(24.29%) for MRSA. This implies that type-5 strains may be less invasive than type-8 strains.
