Pharmacophore an International Research Journal
compound containing two aromatic rings conjunct via bridge system enveloping carbon and keto-ethylenic moiety, considered to be precursors of bioactive flavonoids and isoflavonoids. The molecule owing to presence of dual aromatic rings and keto-ethylenic functionalities act as a versatile and universally accepted lead for search of candidate drug molecule especially anticancer agents. Lower molecular weight, ease of synthetic modification, single step reaction, high yield of pure products are some of the advantages associated with chalcone making it an attractive target for search of better anticancer drug for future. The paper here, thus discuss some of the aspects of chalcone for development of next generation anticancer agents.
