This study aimed to compare emotional regulation skill and health-promoting lifestyle in patients with cardiovascular diseases and normal people in Kerman City. Research method was causal-comparative, and statistical population of this study consisted of 100 cardiovascular patients admitted to Shafa hospital for angiography from September 23, 2015 to November 2015. Statistical population of healthy subjects also consisted of 100 people from patients' families. Data collection was done according to health-promoting lifestyle questionnaire by [1] and Garnefski's Emotional Regulation Skill Questionnaire (2001). Independent t-test was applied for data analysis. According to research findings, there was a significant difference between emotional regulation skill in patients with cardiovascular diseases and normal people. There was also a significant difference between health-promoting lifestyle and components namely physical activity, diet, responsibility, spiritual growth in patients with cardiovascular diseases and normal people. The highest difference was observed between spiritual growth and amount of physical activity in patients with cardiovascular diseases and normal people.