The present study discusses the chemical composition, safety, and efficacy of a dietary supplement with pantohematogen, which is made from the blood of the Altai wapiti. The research methodology focuses on studying the effectiveness of the supplement by assessing the influence of its active ingredients on sports performance. The clinical study targeted professional rowers and mountaineers, whose high-intensity and prolonged training require carefully designed nutrition plans. Pantohematogen demonstrated its effectiveness resulting in improved blood biochemical composition, increased speed, and enhanced performance of rowers; while the positive impact made on mountaineers included better adaptation to high altitude, improved working memory, and better mental and physical capacity. To check compliance with the anti-doping regulations, anti-doping tests were taken and the results were negative. The findings indicate that dietary supplements with pantohematogen can successfully assist in maintaining the proper functioning of the nervous, immune, and cardiovascular systems when included in the nutrition plans of professional athletes.