Pharmacophore an International Research Journal
Introduction: Cerebrovascular disease is the most common neurological disorder. Many studies have been conducted to investigate the effective mechanisms involved in stroke, however, the main pathomecanism in some patients with hemorrhagic stroke has not been known well. The effect of cholesterol level on ischemic stroke has been somewhat proved and much attention has been paid to the impact of it on hemorrhagic stroke. In this study, serum cholesterol levels in patients with hemorrhagic stroke were evaluated.
Methods: The study was cross-sectional and Case-Control. All patients hospitalized with a diagnosis of hemorrhagic stroke in neurology ward of Imam Khomeini Hospital in Urmia Town, Iran, during 2014, were included. Finally, SPSS20 software was used to analyze the data.
Results: In this study, 164 patients were placed in the case group and 356 patients were placed in the control group. There is a significant relationship between the case group and the control group in terms of diabetes, hypertension, smoking, oral contraceptive use, hyperlipidemia, which represents the effects of factors examined in the patients of case group (P-value = 0.002, <0.001, <0.001, <0.001, respectively).
Conclusion: The results showed that diabetes, hypertension, smoking, and use of oral contraceptives can be as risk factors for hemorrhagic stroke. Also, increase in HDL and decrease in cholesterol levels can be as risk factors for hemorrhagic stroke.
