Vegetative vascular dystonia is a common neurological condition characterized by a violation of the regulation of the autonomic nervous system and manifesting various symptoms. In this article, we will focus on hypotonic manifestations in the general structure of vegetative-vascular dystonia and present the results of a statistical analysis based on an extensive sample of patients. The results of our study confirm that hypotonic manifestations are characteristic symptoms of vegetative-vascular dystonia. Our sample of 500 patients with a confirmed diagnosis of vegetative-vascular dystonia allowed us to study these manifestations in more detail. We found that a decrease in blood pressure is an important indicator of hypotonic manifestations in vegetative-vascular dystonia. Measuring blood pressure at rest and during various physical activities allowed us to obtain data on various types of hypotension, such as orthostatic hypotension, postural orthostatic tachycardia, and neurocardiogenic syncopal syndrome. It was also found that weakness and dizziness were the most common symptoms indicating hypotension in patients with vegetative-vascular dystonia.