Pharmacophore an International Research Journal
Periapical lesions brought on by pulpal infections are one of the most specialised conditions in dentistry. The main objective of endodontic therapy is to use chemo-mechanical debridement and root canal filling to significantly reduce or eliminate the microbial load within the root canal system. The objectives of root canal therapy are to eliminate microorganisms from the canal system, remove inflammatory and necrotic pulp tissue, and stop the infection from returning. The teeth's function and aesthetics may be restored and maintained if this is accomplished. The success rate of root canal therapy may exceed 90% when carried out to the highest standards and ranges from 75% to 80% when a periapical lesion is present. One of the most specific disorders in the dentistry sector is periapical lesions brought on by pulpal infections. A systematic literature review from 2011 to 2022 was performed using PubMed, Medline, and ScienceDirect databases. The keywords used were "coronal restoration," "root canal quality," and "periapical status." There were a total of eight studies considered, and the vast majority of them supported the notion that the periapical health of the tooth has a substantial correlation with the effectiveness of root canal therapy and coronal restoration. The effectiveness of root canal therapy and coronal restoration and the frequency of periapical issues are significantly correlated. The presence or absence of an apical radiolucency was statistically related to the effectiveness of endodontic therapy and the presence of a coronal restoration.
