Pharmacophore an International Research Journal
In vitro evaluation of antibacterial activity of aqueous and solvent extract of Mimusops elengi L.(Sapotaceae) was investigated against five pathogenic bacteria viz., Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi , Vibrio cholera and Streptococcus pneumonia at 10,20,30,40 and 50 μl concentration. Among the five pathogen tested, Streptococcus pneumonia and E.coli showed a maximum inhibition of 26.9 mm and 24.4 mm at 50μl concentration compared to standard antibiotics Gentamicin, Tetracycline and Streptomycin. In solvent extract at 10 to 50μl concentration, methanol and ethanol recorded a maximum inhibition of 32.2 mm and 31.3 mm against Streptococcus pneumonia and E.coli. Phytochemical analysis of M. elengi revealed the presence of Tanins, Alkaloids, Saponins, Cardiac glycosides, Steroids, Flavonoids and Reducing sugar.
