The aim is to evaluate the influence of strength and speed exercises on the speed endurance indicators in students, considering the multidirectional load based on the strength of the children’s nervous system. The pedagogical experiment lasted for 3 months in an ordinary school in Russia. The study involved seventh-graders in the number of 40 children aged 13-14 years. In the experimental group, students performed exercises with a differentiated load depending on their typology, which was determined using a tapping test. Strength and speed qualities were evaluated by three tests: long jump, trunk lift, flexion, and extension of the arms. Speed endurance was evaluated by the test – «jump over the rope». After the study, in the control class, in children that have a strong nervous system, indicators of speed-strength improved by 2-3%, and speed-endurance indicators increased by only 8%, and with a weak by 2-4%, and speed-endurance indicators became higher by 6%. The indicators in children from the experimental class in the subgroup that have a strong nervous system improved by 13-14%, and the indicators of speed endurance increased by 19%. In children that have a weak nervous system, the speed-strength qualities indicators increased by 11-16%, and the qualities of speed endurance increased by 23%. If you perform a set of exercises for the development of speed and power abilities in physical education classes at school, both speed-power abilities and the qualities of speed endurance indicators will increase.