Saber Yousefi1, Naser Gharabaghi2, Shohreh Afshar yavari3, Ehsan Soleymannejhad Bari4, Sonya Hasani5
Background: Methicillin-resistant Staphylococcus aureus causes a wide range of serious infections in the hospital and community. The importance of these human pathogens, in addition to its ability in the creation of life-threatening infections, is also its potential for developing antimicrobial resistance. The aim of this study was to determine the minimum inhibitory concentration of Linezolid, Teicoplanin and Vancomycin in methicillin-resistant Staphylococcus aureus isolated from patients admitted to training hospitals of Urmia in 2015-2016.
Methods: In this cross-sectional study, 216 isolates of Staphylococcus aureus isolated from clinical samples (from intensive care unit, urology, pediatric and orthopedic ward), after diagnostic tests 114 isolates of Staphylococcus aureus were isolated. Verified isolates with Linezolid, Teicoplanin and Vancomycin E.Test tapes were investigated through microdilution method and based on CLSI standards.
Results: Of 114 Staphylococcus aureus isolates, 94 isolates (82.45%) were resistant to methicillin and 20 isolates (17.54%) were susceptible to methicillin as well as 88 isolates (93.6%) of methicillin-resistant Staphylococcus aureus were susceptible to all antibiotics and 6 isolates (6.4%) were resistant to all antibiotics. However, none of Staphylococcus aureus strains were not intermediate to all antibiotics.
Conclusion: Methicillin-resistant Staphylococcus aureus is increasingly on the rise. The results of these studies should be available to hospitals in order to be informed of the status of antibiotic resistance in various sectors to adopt basic measures for controlling and eradicating resistant and dangerous strains and preventing the entry of these strains to community by proper and effective planning.
