Pharmacophore an International Research Journal
Objective and layout plan: The project was designed to explore non-enzymatic antioxidants quantities in plants of the Himalayan mountain range, Ayuba, Pakistan. This was aimed at determining their pharmacological potential. After an initial survey, leaves and stem of herbs were collected in three replicas. After proper identification and processing, the extract was prepared in 80 % Methanol. The total alkaloid, Total Phenols, and Flavonoids were determined. The data were subjected to statistical analysis.
Results: The highest amount of total Phenolic contents in leaves of herbs was observed in Impatiens parviflora which was 67.79 mg/g of dry weight. The lowest amount of total phenolic contents was observed in Arisaema wallichianum 12.72 mg/g. The maximum amount of total phenolic contents was noted in the stem of Geranium rotun difolium and the minimum amount of total phenolic contents was found in the stem of Corydalis lutea. Total flavonoid contents in leaves of herbs were 43.38 mg/g in Galium boreale and 17.83 mg/g in Arisaema wallichianum. The maximum quantity of total flavonoids contents in the stem was 43.85 mg/g in Galium boreale and a minimum of 6.05 mg/g was in Impatiens parviflora. The highest quantity of alkaloids in leaves was 78 mg/g in Geranium rotundifolium and the lowest amount of 23.00 mg/g was in Arisaema wallichianum and Artemisia japonica. The maximum quantity of alkaloids in the stem was 58.0 mg/g in Ajuga parviflora and the lowest one was 13 mg/g in Corydalis lutea.
Conclusion: Geranium cotinifolium, Ajugareptans, Aesculusindica, Ajugaparviflora, and Ageratum conyzoidwere proved to have more concentration of Phenolics and alkaloids in their leaves.
