Coccinia indica (Bimba, kanduri, Cucurbitaceae) is famous for its hypoglycemic and antidiabetic properties in Ayurvedic system of medicine. Other applications include the therapy of various conditions such as skin diseases and gonorrhoea. The present review highlights the phytochemistry and pharmacology of Coccinia indica. There are many patented formulations derived from Coccinia indica are now distributed increasingly all over the world. This has given rise to a concomitant increase in research on the phytochemical constituents and biological activity of Coccinia indica.