Pharmacovigilance as An Essential Component of Pharmacotherapy at Tertiary Hospitals in Rural Areas of Pakistan
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Muhammad Naeem Toor, Mirza Tasawer Baig, Shumaila Shaikh, Uzma Shahid, Ambreen Huma, Sadaf Ibrahim, Aisha Jabeen, Nayel Syed, Imran Ali, Samina Sheikh, Hirra Soomro, Shahzada Azam Khan, Arva Rawat, Aiman Syed, Mehwish Murad Ali, Rasheeda Fatima, Faryal Hassan, Javeria Muhammad Arif, Aslam Shah, Saba Shaikh, Jabbar Sheikh
Abstract
Pharmacovigilance (PV) is reporting of ADRs, which may cause increase in hospital stay. All drugs can produce ADRs, but not all patients develop the same level and type of ADRs. The majority of ADRs occur as a result of the extension of the desired pharmacologic effects of a drug, often due to the substantial variability in the pharmacokinetics and pharmacodynamics seen among patients. This study was designed to collect data of ADRs from Tertiary Hospital in Rural Area. This would help the regulatory bodies to implement Pharmacovigilance as an essential component of patient-care. This observational prospective study was conducted at tertiary hospitals to evaluate reporting practices of ARDs using Adverse Drug Reaction Reporting Form of PNPC. From January 2020 to March 2020, thirteen hundred and eighty in-patients from various wards were interviewed after taking their written informed consent. Of the 1380 patients, only 346 informed the Principle Investigator about their experience regarding ADRs. It was concluded that ADRs monitoring and reporting needs to be improved. In rural areas, reporting of ARDs is ignored. DRAP should take drastic steps to ensure reporting of ADRs so that the concept of Pharmacovigilance can be implemented at least at Tertiary Hospitals.
