Berberis lyceum is also known as Indian Barberry. It is a rapidly growing herb mainly distributed in India and Pakistan. In traditional system of medicine, the plant is used for various affliction and diseases. The different parts of the plant like leaves, stem, root, fruits and flowers are used by the people as medicines and food. The plant is known to prevent eye disorders, abdominal disorders, skin diseases etc. Pharmacological investigation has shown that it exhibits antibacterial property, antidiabetic property and cardiac diseases. The Present review article overview the phytochemical and pharmacological properties of the plant and in this article attempt has been made to summarize the anti-inflammatory property of the plant.