Pharmacophore an International Research Journal
About 20% of women after radiation therapy for the presence of malignant neoplasm of the pelvic organs have signs of radiation dysplasia of the mucous membrane of the cervix, in rare cases, the occurrence of these changes in the epithelium of the cervix can be observed in women after treatment of malignant tumors of other organs. This article describes a clinical case of a woman admitted to the Diagnostic Center. The patient had adenomyosis and malignant neoplasm of the left breast with 3 courses of neoadjuvant chemotherapy. The patient's complaints, symptoms of diseases, as well as the results of the conducted studies confirm the presence of radiation dysplasia in her. It is known that changes in cells caused by the treatment of malignant processes are associated with a violation of the synthesis of nucleic acids, inactivation of enzyme systems, chromatin coagulation, mitosis disruption, and transition to amitotic division and denaturation of proteins of the nucleus and cytoplasm, the same thing happens in cells under the influence of ionizing radiation and chemotherapeutic drugs.
