SYNTHESIS AND SCREENING OF 3-((5-((6-(PROPYLYLTHIO)-1H-BENZO[d] IMIDAZOL-2-YL) AMINO)-1, 3, 4-OXADIAZOL-2-YL) IMINO) SUBSTITUTED INDOLIN-2-ONES AS CYTOTOXIC, ANTI-OXIDANT AGENTS Download PDF

The present study involves the synthesis of 3-((5-((6-(propylthio)-1H-Benz [d]imidazol-2-yl) amino)-1, 3, 4-oxadiazol-2-yl)imino) substituted indolin-2-ones and evaluation for their cytotoxic, antioxidant activities. The compounds are screened for their cytotoxicity by MTT assay method for MCF-7, HeLa, HCT-116 and HepG2 cell lines and antioxidant property by DPPH method. All the compounds showed their activity concentration dependent manner.