The effect of 120 & 1000 microgram intracoronary Adenosine on no reflow and ST resolution in STEMI patients Download PDF

Objective: To assess the clinical effectiveness and safety of intracoronary adenosine injection poststenting parameters such as no-reflow, slow flow and ST resolution after percutaneous coronary intervention (PCI).\ Patients and method: Consecutive of 76 patients with a diagnosis of ST-segment elevation myocardial infarction (STEMI) enrolled in this clinical trial study. The patients were divided in to two groups with a simple randomization method. Intra-coronary (IC) bolus adenosine (120-1000 micogram in left coronary artery and 60-500 micogram in right coronary artery) (ICADN) was administered. Statistical analyses were performed with SPSS software for Windows. P values < 0.05 were considered as significant. Results:We studied 76 patients (65 men and 11 women) with ST-segment elevation myocardial infarction (STEMI) candidate for PCI. The mean± SD age was 60.3 ± 12.21 years old (range 28-88 Y/O). According to our data shown in table 3.there was not significant difference between poststenting parameters such as slow-flow, no re-flow and ST resolution when high and low doses of adenosine were administered. Our results revealed administration of different doses of adenosine did not affect on poststenting outcome. Conclusion:According to our results there was not significant difference between poststenting parameters such as slow-flow, no re-flow and ST resolution when high and low doses of adenosine were administered.