Pharmacophore an International Research Journal
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Open Access | Published: 2017 - Issue 3

The effect of Curcuma longa Rhizome Extract on Blood Cells of Mice: An Animal Trial Download PDF

Shahrzad Khakpour, Seyyed mohammad javad Mirlohi, Meisam Akhlaghdoust, Esmaeil Koochak, Nasrin Mohammadi Aref, Hossein Masoodi

Background: The aim of this study is evaluate the effect of hydroalcoholic extract of Turmeric (Curcuma longa) rhizome on blood factors. In traditional medicine, turmeric has been used to treat anemia and strengthening the immune system.

Objectives: In this study, the effect of hydro alcoholic extract of Turmeric rhizome on red blood cells count, white blood cells count, hematocrit, and erythrocyte sedimentation rate (ESR) were studied in mice.

Methods: This animal trial and cross-sectional study was performed in 2015. Animals were tested in five groups of 7 each. Doses of 200 ,400, 600 mg per kg of turmeric extract every day for thirty days were fed through oral feeding to different groups of adult male mice with weighing 20 g to 25 grams. Data was analyzed using SPSS 17 software and presented as mean ± SD.

Results: The results of this study showed that the extract of turmeric rhizome increases red blood cells counts, white blood cells count, hematocrit and percentage of neutrophils and monocytes, but it is ineffective on the erythrocyte sedimentation rate (ESR). The highest response was observed at the dose of 400 mg/kg.

Conclusion: According to the results of this study, it appears that using continuously of turmeric can be relieving anemia and strengthening the immune system.


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ISSN: 2229-5402

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