The purpose of the present study was to investigate, the effect of Language learning strategy use on improving EFL reading comprehension among Iranian Esp. student. It also intended to find out whether there is any interaction between readers' proficiency level and the effectiveness of reading strategy training. A sample of 30 ESP students was chosen and divided into two groups. Fifteen students were males and fifteen were females. They were assigned to experimental (fifteen students) and control groups fifteen students). A quasi experimental research design with a pretest and posttest was used. The study used Oxford’s (1990) Version 7.0 of the SILL, designed for EFL/ESL the reading comprehension test was the second instrument that was used in the present Study and administered to all the participants in both the experimental and the control groups. The background questionnaire was used in order to collect demographic information about Participant’s gender, age and major. The findings of the study indicated that reading strategy training was more effective in improving reading ability of ESP readers than these students who we taught based on the traditional methods of reading instruction. Another major finding was that reading strategy training does not affect the reading ability of learners with different proficiency levels in the same way and those less able readers might benefit more from training