The purpose of this study is to address the relationship between spiritual health and happiness and resilience among the life partners of rehabilitating drug addicts. The research method was non-experimental and correlational. Statistical population was all partners of rehabilitating drug addicts in the city of Shiraz. The number of people who referred to the centers within 2 months is 445 people and according to Morgan table the sample size in this study is 205 subjects and 196 subjects entered the study. A standard questionnaire was used to measure the variables; Palutzian and Ellison's spiritual health questionnaire (1982) is used to measure spiritual health, to measure the resiliency the Connor and Davidson Resilience Scale (2003) is used and to measure happiness the Oxford happiness inventory is applied. For the analysis of data the correlation and regression tests are used. The results showed that spiritual health has a significant relationship with the happiness (R = 0.441) and resilience (R = 0.440) of the partners of rehabilitating drug addicts. In general the results confirmed the hypotheses of the study. In other words, spiritual health coordinates various aspects of life and strengthens mental functions including resilience and happiness.