Vitamin E and Polycystic Ovary Syndrome: A Review on the Reported Clinical Trials Download PDF

Polycystic ovary syndrome is a major gynecological disorder in reproductive-aged women. It is due to the imbalance in the production of sex hormones. Vitamin E is known as the vitamin for reproduction but reports on its effects on reproductive health remain largely understudied. The health benefits of Vit. E on the other body systems, however, have been extensively reported including on its role as an antioxidant, anticancer, anti-proliferative, anti-angiogenic, anti-inflammatory agent, and many more. Since the reports on its benefits on reproductive system are scarce, hence the available reports on the intervention studies specifically on polycystic ovary syndrome (PCOS) are very limited. This paper intended to provide a review on the reported effects of Vit E on PCOS in clinical trials, which could possibly be extended on its importance in future clinical use.

The summary of papers showed that it is still a long way ahead before the mechanisms of actions and outcomes from vitamin E interventions against PCOS could be understood in detail, and yet to suggest the use of vitamin E as one of the natural-based treatment options in the future clinical use.