2026 Volume 17 - Issue 4

1.

Drug Action Has an Address: Spatially Resolved Computational Pharmacology within Heterogeneous Tissue Microenvironments PDF

Pierre Dubois, Marc Lefevre, Claire Moreau, Julien Martin

2026 Issue 4

Downloads: 26

2.

Drug Candidate Has an Environmental Profile before It Becomes a Medicine: Sustainability-Aware Lead Optimization PDF

Nokuthula Dlamini, Sipho Zulu, Thabo Nkosi, Lerato Molefe

2026 Issue 4

Downloads: 35

3.

The Model Evidence Dossier for Traceable, Adaptive, and Change-Controlled Artificial Intelligence in Pharmaceutical Development PDF

Carlos Ramirez, Elena Torres, Pablo Ortega, Sofia Mendes

2026 Issue 4

Downloads: 32

4.

Learning How to Learn from Sparse Assays, Unseen Targets, and Shifting Chemical Spaces in Drug Discovery PDF

Amira Khalil, Sara Fathy, Mahmoud Adel, Hany Nabil

2026 Issue 4

Downloads: 45

5.

Who Is Accountable When an Artificial Intelligence Agent Chooses the Next Pharmaceutical Experiment? PDF

Sven Larsson, Erik Johansson, Anna Nilsson, Lars Andersson

2026 Issue 4

Downloads: 35

6.

From Organ-on-Chip Signals to Human Pharmacology through Mechanistic Translation, Uncertainty Propagation, and Multiscale Modeling PDF

Aisha Bello, Zainab Sule, Ibrahim Musa, Grace Adeyemi

2026 Issue 4

Downloads: 39

7.

Co-Designing mRNA Cargo and Lipid Nanoparticles across Sequence Function, Intracellular Trafficking, Biodistribution, and Manufacturabil PDF

Hassan Ali, Mariam Farooq, Usman Shah, Bilal Khan

2026 Issue 4

Downloads: 33

8.

Counterfactual Dosing with Causal Digital Twins under Patient Heterogeneity, Disease Evolution, and Time-Varying Treatment Response PDF

Grace Collins, Oliver Evans, Noah Williams, Ethan Brooks

2026 Issue 4

Downloads: 36

9.

Designing the Depot Backward from a Target Exposure Profile for Long-Acting Injectable Medicines PDF

Ravi Kumar, Neha Sharma, Aniket Deshmukh, Sanjay Kulkarni

2026 Issue 4

Downloads: 39

10.

Multimodal Generative Artificial Intelligence beyond Molecule Creation: A Scoping Review of Therapeutic Design across Data Modalities PDF

Ali Hassan, Noor Siddiqui, Bilal Khan, Sana Malik

2026 Issue 4

Downloads: 34

11.

Can Pharmaceutical World Models Become Scientific Instruments? A State-of-the-Art Review of Simulation, Reasoning, and Validation PDF

Andreas Müller, Stefan Weber, Julia Hoffmann, Lukas Schneider

2026 Issue 4

Downloads: 36

12.

What Transfers from Molecules to Medicines? A Systematic Review of Foundation Models across Pharmaceutical Scales PDF

James Walker, Olivia Harris, George Wilson

2026 Issue 4

Downloads: 38

13.

When Does a Pharmaceutical Model Become a Digital Twin? An Umbrella Review across Pharmacology, Pharmaceutics, and Drug Delivery PDF

Thabo Nkosi, Lerato Molefe, Sipho Dlamini, Ayanda Mokoena

2026 Issue 4

Downloads: 33

14.

Do Self-Driving Laboratories Accelerate Discovery or Automate Uncertainty, Bias, and Irreproducible Decisions? PDF

Chen Hao, Liu Fang, Zhao Lin, Wei Zhang

2026 Issue 4

Downloads: 39

15.

After the Quantum Advantage Claim: Which Drug-Discovery Problems Are Actually Ready for Quantum Computation? PDF

Lucas Meyer, Anna Schmid, Stefan Braun, Laura Keller

2026 Issue 4

Downloads: 41