Background: Hemodialysis is an essential life-protection strategy in patients with acute kidney injury (AKI) and chronic kidney illness. Between 25% of patients making dialysis using catheters in the first to start with which are invariably removed in patients with AKI. While in the setting of AKI inception of hemodialysis through a catheter is logical to continuation with in Chronic Renal disease patients catheter use must be limited to keep away from its complication. there is consistently reluctance among CKD patients for experiencing arteriovenous (AV) fistula, so the catheter stays in situ for a more extended time in certain patients. This features the need for Individuals awareness among Chronic Renal disease patients. Also, the weak of vascular tree avoid the formation of AV fistula in few CKD patients. For this should be aware of the clinical group for Vein protection in the patient with CKD in Saudi Arabia CKD patients and their doctors should know about possible expected to veins protection and important in the event a new access entrance is required. Aim of the study: To determine the awareness of medical staff for vein saving in the patient with CKD in King Abdul-Aziz Specialist Hospital, King Faisal Hospital, and Armed Forces Hospital, Taif city, KSA. Method: Cross-sectional study will be conducted to determine the awareness of medical staff for vein saving in the patient with CKD in Taif hospitals our total participants were 315 medical staff (doctor, nurses). Results: level of awareness about Patient with history of CKD our study shows that is significant relationship between the Score the level of awareness was the p-value <0.001and Chi-square (X2 -125.19) while ranging were ( 0-6) and Mean± SD (2.041±1.428 ) and the most of participants (47.0%) have Weak awareness about Patient with history of CKD followed by high awareness were (5.1%). Conclusions: Levels of awareness and knowledge among providers must be improved to prevent CKD, its progression, and the vein saving in the patient with CKD. More research is needed to awareness of medical staff for vein saving in the patient with CKD in Saudi Arabia.